Is it human or animal? The origin of pathogenic e. coli in the drinking water of a low-income urban community in bangladesh
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Is it human or animal? The origin of pathogenic e. coli in the drinking water of a low-income urban community in bangladesh. / Ferdous, Jannatul; Rashid, Ridwan Bin; Sultana, Rebeca; Saima, Sabera; Prima, Musharrat Jahan; Begum, Anowara; Jensen, Peter Kjær Mackie.
I: Tropical Medicine and Infectious Disease, Bind 6, Nr. 4, 181, 2021.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Is it human or animal?
T2 - The origin of pathogenic e. coli in the drinking water of a low-income urban community in bangladesh
AU - Ferdous, Jannatul
AU - Rashid, Ridwan Bin
AU - Sultana, Rebeca
AU - Saima, Sabera
AU - Prima, Musharrat Jahan
AU - Begum, Anowara
AU - Jensen, Peter Kjær Mackie
N1 - Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021
Y1 - 2021
N2 - This study aimed to investigate the origin of diverse pathotypes of E. coli, isolated from communal water sources and from the actual drinking water vessel at the point-of-drinking inside households in a low-income urban community in Arichpur, Dhaka, Bangladesh, using a polymerase chain reaction (PCR). Forty-six percent (57/125, CI 95%: 41−58) of the isolates in the point-of-drinking water and 53% (55/103, CI 95%: 45−64) of the isolates in the source water were diarrheagenic E. coli. Among the pathotypes, enterotoxigenic E. coli (ETEC) was the most common, 81% (46/57) of ETEC was found in the point-of-drinking water and 87% (48/55) was found in the communal source water. Phylogenetic group B1, which is predominant in animals, was the most frequently found isolate in both the point-of-drinking water (50%, 91/181) and in the source (50%, 89/180) water. The phylogenetic subgroup B23, usually of human origin, was more common in the point-of-drinking water (65%, 13/20) than in the source water (35%, 7/20). Our findings suggest that non-human mammals and birds played a vital role in fecal contamination for both the source and point-of-drinking water. Addressing human sanitation without a consideration of fecal contamination from livestock sources will not be enough to prevent drinking-water contamination and thus will persist as a greater contributor to diarrheal pathogens.
AB - This study aimed to investigate the origin of diverse pathotypes of E. coli, isolated from communal water sources and from the actual drinking water vessel at the point-of-drinking inside households in a low-income urban community in Arichpur, Dhaka, Bangladesh, using a polymerase chain reaction (PCR). Forty-six percent (57/125, CI 95%: 41−58) of the isolates in the point-of-drinking water and 53% (55/103, CI 95%: 45−64) of the isolates in the source water were diarrheagenic E. coli. Among the pathotypes, enterotoxigenic E. coli (ETEC) was the most common, 81% (46/57) of ETEC was found in the point-of-drinking water and 87% (48/55) was found in the communal source water. Phylogenetic group B1, which is predominant in animals, was the most frequently found isolate in both the point-of-drinking water (50%, 91/181) and in the source (50%, 89/180) water. The phylogenetic subgroup B23, usually of human origin, was more common in the point-of-drinking water (65%, 13/20) than in the source water (35%, 7/20). Our findings suggest that non-human mammals and birds played a vital role in fecal contamination for both the source and point-of-drinking water. Addressing human sanitation without a consideration of fecal contamination from livestock sources will not be enough to prevent drinking-water contamination and thus will persist as a greater contributor to diarrheal pathogens.
KW - Diarrhea
KW - Drinking water
KW - Escherichia coli pathotypes
KW - ETEC
KW - One health
KW - Phylogenetic
U2 - 10.3390/tropicalmed6040181
DO - 10.3390/tropicalmed6040181
M3 - Journal article
C2 - 34698298
AN - SCOPUS:85117181729
VL - 6
JO - Tropical Medicine and Infectious Disease
JF - Tropical Medicine and Infectious Disease
SN - 2414-6366
IS - 4
M1 - 181
ER -
ID: 282601834