Integrin signaling to the actin cytoskeleton
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
Integrin engagement stimulates the activity of numerous signaling molecules, including the Rho family of GTPases, tyrosine phosphatases, cAMP-dependent protein kinase and protein kinase C, and stimulates production of PtdIns(4,5)P2. Integrins promote actin assembly via the recruitment of molecules that directly activate the actin polymerization machinery or physically link it to sites of cell adhesion.
Originalsprog | Engelsk |
---|---|
Tidsskrift | Current Opinion in Cell Biology |
Vol/bind | 15 |
Udgave nummer | 5 |
Sider (fra-til) | 572-82 |
Antal sider | 11 |
ISSN | 0955-0674 |
Status | Udgivet - okt. 2003 |
Eksternt udgivet | Ja |
ID: 199433219