Individualisering af behandling af osteoartikulære infektioner hos børn kan afkorte behandlingsforløbet
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Individualisering af behandling af osteoartikulære infektioner hos børn kan afkorte behandlingsforløbet. / Kristensen, Kim; Andersen, Jesper; Hansen, Kjeld Gade; Hoffmann, Thomas; Kurtzhals, Jørgen; Nygaard, Ulrikka; Pedersen, Freddy Karup.
I: Ugeskrift for Laeger, Bind 176, Nr. 30, 21.07.2014.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Individualisering af behandling af osteoartikulære infektioner hos børn kan afkorte behandlingsforløbet
AU - Kristensen, Kim
AU - Andersen, Jesper
AU - Hansen, Kjeld Gade
AU - Hoffmann, Thomas
AU - Kurtzhals, Jørgen
AU - Nygaard, Ulrikka
AU - Pedersen, Freddy Karup
PY - 2014/7/21
Y1 - 2014/7/21
N2 - Older studies have suggested that antibiotic treatment for less than 21 days in children with osteoarticular infections is associated with relapse, and therefore traditionally these infections have been treated for six weeks with an intravenous phase of one week. However, four new prospective studies suggest that if the duration of treatment is individualized and made dependent on the clinical response and the C-reactive protein level, the treatment course may be shortened substantially without increasing the risk of relapse or sequelae. This article reviews older and newer literature on this subject.
AB - Older studies have suggested that antibiotic treatment for less than 21 days in children with osteoarticular infections is associated with relapse, and therefore traditionally these infections have been treated for six weeks with an intravenous phase of one week. However, four new prospective studies suggest that if the duration of treatment is individualized and made dependent on the clinical response and the C-reactive protein level, the treatment course may be shortened substantially without increasing the risk of relapse or sequelae. This article reviews older and newer literature on this subject.
M3 - Tidsskriftartikel
C2 - 25292233
VL - 176
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 30
ER -
ID: 135120253