Increasing the reference populations for the 55 AISNP panel: the need and benefits
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Increasing the reference populations for the 55 AISNP panel : the need and benefits. / Pakstis, Andrew J; Kang, Longli; Liu, Lijun; Zhang, Zhiying; Jin, Tianbo; Grigorenko, Elena L; Wendt, Frank R; Budowle, Bruce; Hadi, Sibte; Al Qahtani, Mariam Salam; Morling, Niels; Mogensen, Helle Smidt; Themudo, Goncalo E; Soundararajan, Usha; Rajeevan, Haseena; Kidd, Judith R; Kidd, Kenneth K.
I: International Journal of Legal Medicine, Bind 131, Nr. 4, 2017, s. 913–917.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Increasing the reference populations for the 55 AISNP panel
T2 - the need and benefits
AU - Pakstis, Andrew J
AU - Kang, Longli
AU - Liu, Lijun
AU - Zhang, Zhiying
AU - Jin, Tianbo
AU - Grigorenko, Elena L
AU - Wendt, Frank R
AU - Budowle, Bruce
AU - Hadi, Sibte
AU - Al Qahtani, Mariam Salam
AU - Morling, Niels
AU - Mogensen, Helle Smidt
AU - Themudo, Goncalo E
AU - Soundararajan, Usha
AU - Rajeevan, Haseena
AU - Kidd, Judith R
AU - Kidd, Kenneth K
PY - 2017
Y1 - 2017
N2 - Ancestry inference for an individual can only be as good as the reference populations with allele frequency data on the SNPs being used. If the most relevant ancestral population(s) does not have data available for the SNPs studied, then analyses based on DNA evidence may indicate a quite distantly related population, albeit one among the more closely related of the existing reference populations. We have added reference population allele frequencies for 14 additional population samples (with >1100 individuals studied) to the 125 population samples previously published for the Kidd Lab 55 AISNP panel. Allele frequencies are now publicly available for all 55 SNPs in ALFRED and FROG-kb for a total of 139 population samples. This Kidd Lab panel of 55 ancestry informative SNPs has been incorporated in commercial kits by both ThermoFisher Scientific and Illumina for massively parallel sequencing. Researchers employing those kits will find the enhanced set of reference populations useful.
AB - Ancestry inference for an individual can only be as good as the reference populations with allele frequency data on the SNPs being used. If the most relevant ancestral population(s) does not have data available for the SNPs studied, then analyses based on DNA evidence may indicate a quite distantly related population, albeit one among the more closely related of the existing reference populations. We have added reference population allele frequencies for 14 additional population samples (with >1100 individuals studied) to the 125 population samples previously published for the Kidd Lab 55 AISNP panel. Allele frequencies are now publicly available for all 55 SNPs in ALFRED and FROG-kb for a total of 139 population samples. This Kidd Lab panel of 55 ancestry informative SNPs has been incorporated in commercial kits by both ThermoFisher Scientific and Illumina for massively parallel sequencing. Researchers employing those kits will find the enhanced set of reference populations useful.
U2 - 10.1007/s00414-016-1524-z
DO - 10.1007/s00414-016-1524-z
M3 - Journal article
C2 - 28070634
VL - 131
SP - 913
EP - 917
JO - International Journal of Legal Medicine
JF - International Journal of Legal Medicine
SN - 0937-9827
IS - 4
ER -
ID: 172431435