Increasing seroprevalence of Clostridium difficile in an adult Danish general population

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

Increasing seroprevalence of Clostridium difficile in an adult Danish general population. / Fenger, R V; Linneberg, A; Tvede, M; Ostergaard, C.

I: Epidemiology and Infection, Bind 137, Nr. 2, 2009, s. 278-83.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Fenger, RV, Linneberg, A, Tvede, M & Ostergaard, C 2009, 'Increasing seroprevalence of Clostridium difficile in an adult Danish general population', Epidemiology and Infection, bind 137, nr. 2, s. 278-83. https://doi.org/10.1017/S0950268808000800

APA

Fenger, R. V., Linneberg, A., Tvede, M., & Ostergaard, C. (2009). Increasing seroprevalence of Clostridium difficile in an adult Danish general population. Epidemiology and Infection, 137(2), 278-83. https://doi.org/10.1017/S0950268808000800

Vancouver

Fenger RV, Linneberg A, Tvede M, Ostergaard C. Increasing seroprevalence of Clostridium difficile in an adult Danish general population. Epidemiology and Infection. 2009;137(2):278-83. https://doi.org/10.1017/S0950268808000800

Author

Fenger, R V ; Linneberg, A ; Tvede, M ; Ostergaard, C. / Increasing seroprevalence of Clostridium difficile in an adult Danish general population. I: Epidemiology and Infection. 2009 ; Bind 137, Nr. 2. s. 278-83.

Bibtex

@article{780c5d3005d611deb05e000ea68e967b,
title = "Increasing seroprevalence of Clostridium difficile in an adult Danish general population",
abstract = "The incidence of Clostridium difficile-associated infections is increasing, but it remains to be defined whether any change in the seroprevalence of C. difficile has also occurred. In a population-based study of the general adult population, 734 subjects, aged 15-69 years, were examined on two occasions 8 years apart (1990 and 1998) for the presence of antibodies against C. difficile in serum. The overall seroprevalence of C. difficile increased significantly from 19% in 1990 to 27% in 1998 (P<0.0001). The seroprevalence increased with increasing age in both 1990 and 1998, but the increase was about four times higher in 1998 than in 1990. In conclusion, the observed increase in seroprevalence suggests a higher exposure to C. difficile in the general Danish adult population.",
author = "Fenger, {R V} and A Linneberg and M Tvede and C Ostergaard",
note = "Keywords: Adolescent; Adult; Aged; Antibodies, Bacterial; Clostridium difficile; Denmark; Humans; Middle Aged; Seroepidemiologic Studies; Young Adult",
year = "2009",
doi = "10.1017/S0950268808000800",
language = "English",
volume = "137",
pages = "278--83",
journal = "Epidemiology and Infection",
issn = "0950-2688",
publisher = "Cambridge University Press",
number = "2",

}

RIS

TY - JOUR

T1 - Increasing seroprevalence of Clostridium difficile in an adult Danish general population

AU - Fenger, R V

AU - Linneberg, A

AU - Tvede, M

AU - Ostergaard, C

N1 - Keywords: Adolescent; Adult; Aged; Antibodies, Bacterial; Clostridium difficile; Denmark; Humans; Middle Aged; Seroepidemiologic Studies; Young Adult

PY - 2009

Y1 - 2009

N2 - The incidence of Clostridium difficile-associated infections is increasing, but it remains to be defined whether any change in the seroprevalence of C. difficile has also occurred. In a population-based study of the general adult population, 734 subjects, aged 15-69 years, were examined on two occasions 8 years apart (1990 and 1998) for the presence of antibodies against C. difficile in serum. The overall seroprevalence of C. difficile increased significantly from 19% in 1990 to 27% in 1998 (P<0.0001). The seroprevalence increased with increasing age in both 1990 and 1998, but the increase was about four times higher in 1998 than in 1990. In conclusion, the observed increase in seroprevalence suggests a higher exposure to C. difficile in the general Danish adult population.

AB - The incidence of Clostridium difficile-associated infections is increasing, but it remains to be defined whether any change in the seroprevalence of C. difficile has also occurred. In a population-based study of the general adult population, 734 subjects, aged 15-69 years, were examined on two occasions 8 years apart (1990 and 1998) for the presence of antibodies against C. difficile in serum. The overall seroprevalence of C. difficile increased significantly from 19% in 1990 to 27% in 1998 (P<0.0001). The seroprevalence increased with increasing age in both 1990 and 1998, but the increase was about four times higher in 1998 than in 1990. In conclusion, the observed increase in seroprevalence suggests a higher exposure to C. difficile in the general Danish adult population.

U2 - 10.1017/S0950268808000800

DO - 10.1017/S0950268808000800

M3 - Journal article

C2 - 18503728

VL - 137

SP - 278

EP - 283

JO - Epidemiology and Infection

JF - Epidemiology and Infection

SN - 0950-2688

IS - 2

ER -

ID: 10928102