Increased blood BDNF in healthy individuals with a family history of depression
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Increased blood BDNF in healthy individuals with a family history of depression. / Knorr, Ulla; Søndergaard, Mia H Greisen; Koefoed, Pernille; Jørgensen, Anders; Faurholt-Jepsen, Maria; Vinberg, Maj; Kessing, Lars Vedel.
I: Psychiatry Research, Bind 256, 2017, s. 176-179.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Increased blood BDNF in healthy individuals with a family history of depression
AU - Knorr, Ulla
AU - Søndergaard, Mia H Greisen
AU - Koefoed, Pernille
AU - Jørgensen, Anders
AU - Faurholt-Jepsen, Maria
AU - Vinberg, Maj
AU - Kessing, Lars Vedel
N1 - Copyright © 2017 Elsevier B.V. All rights reserved.
PY - 2017
Y1 - 2017
N2 - The brain-derive neurotrophic factor (BDNF) may play an important role in the course of depression. We aimed to study the associations between peripheral whole blood BDNF levels in healthy individuals with and without a family history of depression. BDNF levels were significantly increased in healthy individuals with (n = 76), compared with healthy individuals without (n = 39) a family history of depression and persisted after adjustment for age and gender differences. Higher BDNF levels were associated with increasing age and seasonality. A family history of depression may contribute to an elevation of peripheral BDNF levels in healthy individuals.
AB - The brain-derive neurotrophic factor (BDNF) may play an important role in the course of depression. We aimed to study the associations between peripheral whole blood BDNF levels in healthy individuals with and without a family history of depression. BDNF levels were significantly increased in healthy individuals with (n = 76), compared with healthy individuals without (n = 39) a family history of depression and persisted after adjustment for age and gender differences. Higher BDNF levels were associated with increasing age and seasonality. A family history of depression may contribute to an elevation of peripheral BDNF levels in healthy individuals.
U2 - 10.1016/j.psychres.2017.06.057
DO - 10.1016/j.psychres.2017.06.057
M3 - Journal article
C2 - 28645077
VL - 256
SP - 176
EP - 179
JO - Psychiatry Research
JF - Psychiatry Research
SN - 0165-1781
ER -
ID: 194804191