Incidence of infective endocarditis during the coronavirus disease 2019 pandemic: A nationwide study
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Standard
Incidence of infective endocarditis during the coronavirus disease 2019 pandemic : A nationwide study. / Havers-Borgersen, Eva; Fosbøl, Emil L.; Butt, Jawad H.; Petersen, Jeppe K.; Dalsgaard, Andreas; Kyhl, Frederik; Schou, Morten; Phelps, Matthew; Kragholm, Kristian; Gislason, Gunnar H.; Torp-Pedersen, Christian; Køber, Lars; Østergaard, Lauge.
I: IJC Heart and Vasculature, Bind 31, 100675, 2020.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Incidence of infective endocarditis during the coronavirus disease 2019 pandemic
T2 - A nationwide study
AU - Havers-Borgersen, Eva
AU - Fosbøl, Emil L.
AU - Butt, Jawad H.
AU - Petersen, Jeppe K.
AU - Dalsgaard, Andreas
AU - Kyhl, Frederik
AU - Schou, Morten
AU - Phelps, Matthew
AU - Kragholm, Kristian
AU - Gislason, Gunnar H.
AU - Torp-Pedersen, Christian
AU - Køber, Lars
AU - Østergaard, Lauge
PY - 2020
Y1 - 2020
N2 - Background: The incidence of infective endocarditis (IE) has increased in recent decades. Societal lockdown including reorganization of the healthcare system during the COVID-19 pandemic may influence the incidence of IE. This study sets out to investigate the incidence of IE during the Danish national lockdown. Methods: In this nationwide cohort study, patients admitted with IE in either one of two periods A) A combined period of 1 January to 7 May for 2018 and 2019, or B) 1 January to 6 May 2020, were identified using Danish nationwide registries. Weekly incidence rates of IE admissions for the 2018/2019-period and 2020-period were computed and incidence rate ratios (IRR) for 2020-incidence vs 2018/2019-incidence were calculated using Poisson regression analysis. Results: In total, 208 (67.3% men, median age 74.1 years) and 429 (64.1% men, median age 72.7 years) patients were admitted with IE in 2020 and 2018/2019, respectively. No significant difference in incidence rates were found comparing the 2020-period and 2018/2019-period (IRR: 0.96 (95% CI: 0.82–1.14). The overall incidence rate pre-lockdown (week 1–10: 1 January to 11 March 2020) was 14.2 IE cases per 100,000 person years (95% CI: 12.0–16.9) as compared with 11.4 IE cases per 100,000 person years (95% CI: 9.1–14.1) during lockdown (week 11–18: 12 March to 6 May 2020) corresponding to an IRR of 0.80 (95% CI: 0.60–1.06) and thus no significant difference pre- versus post-lockdown. Conclusion: In this nationwide cohort study, no significant difference in the incidence of IE admissions during the national lockdown due to the COVID-19 pandemic was found.
AB - Background: The incidence of infective endocarditis (IE) has increased in recent decades. Societal lockdown including reorganization of the healthcare system during the COVID-19 pandemic may influence the incidence of IE. This study sets out to investigate the incidence of IE during the Danish national lockdown. Methods: In this nationwide cohort study, patients admitted with IE in either one of two periods A) A combined period of 1 January to 7 May for 2018 and 2019, or B) 1 January to 6 May 2020, were identified using Danish nationwide registries. Weekly incidence rates of IE admissions for the 2018/2019-period and 2020-period were computed and incidence rate ratios (IRR) for 2020-incidence vs 2018/2019-incidence were calculated using Poisson regression analysis. Results: In total, 208 (67.3% men, median age 74.1 years) and 429 (64.1% men, median age 72.7 years) patients were admitted with IE in 2020 and 2018/2019, respectively. No significant difference in incidence rates were found comparing the 2020-period and 2018/2019-period (IRR: 0.96 (95% CI: 0.82–1.14). The overall incidence rate pre-lockdown (week 1–10: 1 January to 11 March 2020) was 14.2 IE cases per 100,000 person years (95% CI: 12.0–16.9) as compared with 11.4 IE cases per 100,000 person years (95% CI: 9.1–14.1) during lockdown (week 11–18: 12 March to 6 May 2020) corresponding to an IRR of 0.80 (95% CI: 0.60–1.06) and thus no significant difference pre- versus post-lockdown. Conclusion: In this nationwide cohort study, no significant difference in the incidence of IE admissions during the national lockdown due to the COVID-19 pandemic was found.
KW - COVID-19
KW - Epidemiology
KW - Infective endocarditis
KW - Pandemic
UR - http://www.scopus.com/inward/record.url?scp=85097390728&partnerID=8YFLogxK
U2 - 10.1016/j.ijcha.2020.100675
DO - 10.1016/j.ijcha.2020.100675
M3 - Journal article
C2 - 33235900
AN - SCOPUS:85097390728
VL - 31
JO - IJC Heart and Vasculature
JF - IJC Heart and Vasculature
SN - 2352-9067
M1 - 100675
ER -
ID: 255406698