TY - JOUR

T1 - Impaired Saccadic Eye Movement in Primary Open-angle Glaucoma

AU - Lamirel, Cédric

AU - Milea, Dan

AU - Cochereau, Isabelle

AU - Duong, Minh-Hanh

AU - Lorenceau, Jean

PY - 2013

Y1 - 2013

N2 - PURPOSE:: Our study aimed at investigating the extent to which saccadic eye movements are disrupted in patients with primary open-angle glaucoma (POAG). This approach followed upon the discovery of differences in the eye-movement behavior of POAG patients during the exploration of complex visual scenes. METHODS:: The eye movements of 8 POAG patients and 4 healthy age-matched controls were recorded. Four of the patients had documented visual field scotoma, and 4 had no identifiable scotoma on visual field testing. The eye movements were monitored as the observers watched static and kinetic targets. The gain, latency, and velocity-peak latency of the saccades recorded were then analyzed. RESULTS:: In POAG patients, with abnormal visual fields, watching a static target, the saccades were delayed and their accuracy was reduced, compared with those of normal observers. In POAG patients, with normal and abnormal visual fields, watching a kinetic target, a task involving precise motion analysis, the latency and accuracy of the saccades were impaired, compared with those of normal observers. CONCLUSIONS:: Our findings suggest that POAG alters saccade programming and execution particularly in the case of moving targets.

AB - PURPOSE:: Our study aimed at investigating the extent to which saccadic eye movements are disrupted in patients with primary open-angle glaucoma (POAG). This approach followed upon the discovery of differences in the eye-movement behavior of POAG patients during the exploration of complex visual scenes. METHODS:: The eye movements of 8 POAG patients and 4 healthy age-matched controls were recorded. Four of the patients had documented visual field scotoma, and 4 had no identifiable scotoma on visual field testing. The eye movements were monitored as the observers watched static and kinetic targets. The gain, latency, and velocity-peak latency of the saccades recorded were then analyzed. RESULTS:: In POAG patients, with abnormal visual fields, watching a static target, the saccades were delayed and their accuracy was reduced, compared with those of normal observers. In POAG patients, with normal and abnormal visual fields, watching a kinetic target, a task involving precise motion analysis, the latency and accuracy of the saccades were impaired, compared with those of normal observers. CONCLUSIONS:: Our findings suggest that POAG alters saccade programming and execution particularly in the case of moving targets.

U2 - 10.1097/IJG.0b013e31825c10dc

DO - 10.1097/IJG.0b013e31825c10dc

M3 - Journal article

C2 - 22706338

JO - Journal of Glaucoma

JF - Journal of Glaucoma

SN - 1057-0829

ER -