Impact of psychological stress on the associations between apolipoprotein E variants and metabolic traits: findings in an American sample of caregivers and controls
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
To examine the association between apolipoprotein E (APOE) gene variants and waist circumference, fasting plasma glucose, serum insulin, serum high-density lipoprotein cholesterol, and serum triglycerides, all metabolic traits known as cardiovascular disease (CVD) endophenotypes, in a population of stressed individuals and controls. Abdominal obesity, insulin resistance, elevated serum lipid concentration, and APOE polymorphisms have been associated with CVD risk. Current evidence supports the hypothesis that gene-environment interactions modulate serum lipid concentrations.
Originalsprog | Engelsk |
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Tidsskrift | Psychosomatic Medicine |
Vol/bind | 72 |
Udgave nummer | 5 |
Sider (fra-til) | 427-33 |
Antal sider | 7 |
ISSN | 0033-3174 |
DOI | |
Status | Udgivet - 1 jun. 2010 |
ID: 40208312