Impact of pre-admission depression on mortality following myocardial infarction
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Impact of pre-admission depression on mortality following myocardial infarction. / Sundbøll, Jens; Schmidt, Morten; Adelborg, Kasper; Pedersen, Lars; Bøtker, Hans Erik; Videbech, Poul; Sørensen, Henrik Toft.
I: The British journal of psychiatry : the journal of mental science, Bind 210, Nr. 5, 2017, s. 356-361.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Impact of pre-admission depression on mortality following myocardial infarction
AU - Sundbøll, Jens
AU - Schmidt, Morten
AU - Adelborg, Kasper
AU - Pedersen, Lars
AU - Bøtker, Hans Erik
AU - Videbech, Poul
AU - Sørensen, Henrik Toft
N1 - © The Royal College of Psychiatrists 2017.
PY - 2017
Y1 - 2017
N2 - BackgroundThe prognostic impact of previous depression on myocardial infarction survival remains poorly understood.AimsTo examine the association between depression and all-cause mortality following myocardial infarction.MethodUsing Danish medical registries, we conducted a nationwide population-based cohort study. We included all patients with first-time myocardial infarction (1995-2014) and identified previous depression as either a depression diagnosis or use of antidepressants. We used Cox regression to compute adjusted mortality rate ratios (aMRRs) with 95% confidence intervals.ResultsWe identified 170 771 patients with first-time myocardial infarction. Patients with myocardial infarction and a previous depression diagnosis had higher 19-year mortality risks (87% v. 78%). The overall aMRR was 1.11 (95% CI 1.07-1.15) increasing to 1.22 (95% CI 1.17-1.27) when including use of antidepressants in the depression definition.ConclusionsA history of depression was associated with a moderately increased all-cause mortality following myocardial infarction.
AB - BackgroundThe prognostic impact of previous depression on myocardial infarction survival remains poorly understood.AimsTo examine the association between depression and all-cause mortality following myocardial infarction.MethodUsing Danish medical registries, we conducted a nationwide population-based cohort study. We included all patients with first-time myocardial infarction (1995-2014) and identified previous depression as either a depression diagnosis or use of antidepressants. We used Cox regression to compute adjusted mortality rate ratios (aMRRs) with 95% confidence intervals.ResultsWe identified 170 771 patients with first-time myocardial infarction. Patients with myocardial infarction and a previous depression diagnosis had higher 19-year mortality risks (87% v. 78%). The overall aMRR was 1.11 (95% CI 1.07-1.15) increasing to 1.22 (95% CI 1.17-1.27) when including use of antidepressants in the depression definition.ConclusionsA history of depression was associated with a moderately increased all-cause mortality following myocardial infarction.
KW - Adult
KW - Aged
KW - Aged, 80 and over
KW - Denmark/epidemiology
KW - Depressive Disorder/complications
KW - Female
KW - Humans
KW - Kaplan-Meier Estimate
KW - Male
KW - Middle Aged
KW - Myocardial Infarction/mortality
KW - Prognosis
KW - Prospective Studies
KW - Risk Factors
U2 - 10.1192/bjp.bp.116.194605
DO - 10.1192/bjp.bp.116.194605
M3 - Journal article
C2 - 28254961
VL - 210
SP - 356
EP - 361
JO - The Journal of mental science
JF - The Journal of mental science
SN - 0960-5371
IS - 5
ER -
ID: 196141887