Immigration of susceptible hosts triggers the evolution of alternative parasite defence strategies
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Immigration of susceptible hosts triggers the evolution of alternative parasite defence strategies. / Chabas, Hélène; van Houte, Stineke; Høyland-Kroghsbo, Nina Molin; Buckling, Angus; Westra, Edze R.
I: Proceedings. Biological sciences / The Royal Society, Bind 283, Nr. 1837, 2016.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Immigration of susceptible hosts triggers the evolution of alternative parasite defence strategies
AU - Chabas, Hélène
AU - van Houte, Stineke
AU - Høyland-Kroghsbo, Nina Molin
AU - Buckling, Angus
AU - Westra, Edze R
N1 - © 2016 The Author(s).
PY - 2016
Y1 - 2016
N2 - Migration of hosts and parasites can have a profound impact on host-parasite ecological and evolutionary interactions. Using the bacterium Pseudomonas aeruginosa UCBPP-PA14 and its phage DMS3vir, we here show that immigration of naive hosts into coevolving populations of hosts and parasites can influence the mechanistic basis underlying host defence evolution. Specifically, we found that at high levels of bacterial immigration, bacteria switched from clustered regularly interspaced short palindromic repeats (CRISPR-Cas) to surface modification-mediated defence. This effect emerges from an increase in the force of infection, which tips the balance from CRISPR to surface modification-based defence owing to the induced and fixed fitness costs associated with these mechanisms, respectively.
AB - Migration of hosts and parasites can have a profound impact on host-parasite ecological and evolutionary interactions. Using the bacterium Pseudomonas aeruginosa UCBPP-PA14 and its phage DMS3vir, we here show that immigration of naive hosts into coevolving populations of hosts and parasites can influence the mechanistic basis underlying host defence evolution. Specifically, we found that at high levels of bacterial immigration, bacteria switched from clustered regularly interspaced short palindromic repeats (CRISPR-Cas) to surface modification-mediated defence. This effect emerges from an increase in the force of infection, which tips the balance from CRISPR to surface modification-based defence owing to the induced and fixed fitness costs associated with these mechanisms, respectively.
KW - Journal Article
U2 - 10.1098/rspb.2016.0721
DO - 10.1098/rspb.2016.0721
M3 - Journal article
C2 - 27581884
VL - 283
JO - Proceedings of the Royal Society B: Biological Sciences
JF - Proceedings of the Royal Society B: Biological Sciences
SN - 0962-8452
IS - 1837
ER -
ID: 165395708