How first-episode psychosis patients' subjective beliefs about their childhood trauma's causal effect provide support for potential schizophrenia subtypes

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • Julie Perrine Schaug
  • Ole Jakob Storebø
  • Marlene Buch Pedersen
  • Ulrik Helt Haahr
  • Simonsen, Erik
Background
Childhood and adolescent trauma is a risk factor for developing psychosis-spectrum disorders. The current study aimed to assess how childhood trauma might predict psychosis symptomatology, and how patients' beliefs of whether trauma is the cause of psychosis might affect this association.

Methods
Ninety-six first-episode psychosis patients were assessed for childhood traumatic experiences with the Brief Betrayal Trauma Survey, and for psychosis symptoms with the Positive and Negative Syndrome Scale.

Results
Non-interpersonal trauma predicted higher positive symptoms, whereas more trauma domains experienced predicted lower negative symptoms. Almost half of the participants believed trauma to be related to psychosis, were 12 times more likely to reexperience trauma through psychosis, and had higher excitative and emotional symptoms. Non-interpersonal trauma also predicted higher positive symptoms in this group. Those who did not believe trauma to be the cause of psychosis had higher negative symptoms, and a negative dose-response was found for negative and disorganised symptoms, in which more trauma domains experienced predicted lower scores.

Conclusions
Results imply two traumagenic pathways to psychosis, one characterised by positive, excitative, and emotional symptoms, and one negative subtype, characterised by negative and disorganised symptoms. Clinical implications for how findings might contribute to better treatments are discussed.
OriginalsprogEngelsk
TidsskriftSchizophrenia Research
Vol/bind262
Sider (fra-til)175-183
Antal sider9
ISSN0920-9964
DOI
StatusUdgivet - 2023

Bibliografisk note

Funding Information:
This study was supported by the Region Zealand Health Scientific Research Foundation and the Psychiatric Research Unit, Psychiatric Services Region Zealand , 4200 Slagelse, Denmark. No external funding was received.

Publisher Copyright:
© 2023 Elsevier B.V.

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