High incidence of amyotrophic lateral sclerosis in the Faroe Islands 2010–2020
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High incidence of amyotrophic lateral sclerosis in the Faroe Islands 2010–2020. / Johansen, Malan; Svenstrup, Kirsten; Joensen, Poul; Steig, Bjarni; Andorsdóttir, Guðrið; Hansen, Torben; Petersen, Maria Skaalum.
I: Annals of Clinical and Translational Neurology, Bind 9, Nr. 2, 2022, s. 227-231.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - High incidence of amyotrophic lateral sclerosis in the Faroe Islands 2010–2020
AU - Johansen, Malan
AU - Svenstrup, Kirsten
AU - Joensen, Poul
AU - Steig, Bjarni
AU - Andorsdóttir, Guðrið
AU - Hansen, Torben
AU - Petersen, Maria Skaalum
N1 - Publisher Copyright: © 2022 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals LLC on behalf of American Neurological Association.
PY - 2022
Y1 - 2022
N2 - The Faroese population isolate harbors epidemiological and genetic characteristics that likely differ from outbred populations. This population-based register study found that the Faroese 2010–2020 crude incidence of amyotrophic lateral sclerosis (ALS) was 4.9/100,000 person-years (95% confidence interval [CI], 3.3–7.0) and the age- and sex-standardized incidence (US 2010 Census Population) was 4.1/100,000 person-years (95% CI, 2.7–6.0), which is a 68% increase from the 1987–2009 estimate. The 2020 crude prevalence was 9.5/100,000 (95% CI, 3.0–19.6) in a population of 52,912 inhabitants. Incidence and prevalence estimates of ALS in the Faroes are high and further research is warranted to uncover the genetic or environmental determinants of ALS in this population.
AB - The Faroese population isolate harbors epidemiological and genetic characteristics that likely differ from outbred populations. This population-based register study found that the Faroese 2010–2020 crude incidence of amyotrophic lateral sclerosis (ALS) was 4.9/100,000 person-years (95% confidence interval [CI], 3.3–7.0) and the age- and sex-standardized incidence (US 2010 Census Population) was 4.1/100,000 person-years (95% CI, 2.7–6.0), which is a 68% increase from the 1987–2009 estimate. The 2020 crude prevalence was 9.5/100,000 (95% CI, 3.0–19.6) in a population of 52,912 inhabitants. Incidence and prevalence estimates of ALS in the Faroes are high and further research is warranted to uncover the genetic or environmental determinants of ALS in this population.
U2 - 10.1002/acn3.51501
DO - 10.1002/acn3.51501
M3 - Journal article
C2 - 35048555
AN - SCOPUS:85123002628
VL - 9
SP - 227
EP - 231
JO - Annals of Clinical and Translational Neurology
JF - Annals of Clinical and Translational Neurology
SN - 2328-9503
IS - 2
ER -
ID: 290596931