Persistent pain following groin hernia repair (PPGH) is seen in 2-4% of patients leading to functional and socioeconomic disability. A Danish research unit for PPHG was established in 2010 in collaboration with anaesthetists and surgeons. More than 140 patients have been examined with clinical and electrophysiological methods. Published data on 54 patients, treated with mesh removal and selective neurectomy, demonstrated that 65% patients experienced long-term reduction of pain. The PPHG unit is actively engaged in surgical and pharmacological research in order to improve treatment strategies.