Gut-Brain Cross-Talk in Metabolic Control

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Standard

Gut-Brain Cross-Talk in Metabolic Control. / Clemmensen, Christoffer; Müller, Timo D; Woods, Stephen C; Berthoud, Hans-Rudolf; Seeley, Randy J; Tschöp, Matthias H.

I: Cell, Bind 168, Nr. 5, 23.02.2017, s. 758-774.

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Harvard

Clemmensen, C, Müller, TD, Woods, SC, Berthoud, H-R, Seeley, RJ & Tschöp, MH 2017, 'Gut-Brain Cross-Talk in Metabolic Control', Cell, bind 168, nr. 5, s. 758-774. https://doi.org/10.1016/j.cell.2017.01.025

APA

Clemmensen, C., Müller, T. D., Woods, S. C., Berthoud, H-R., Seeley, R. J., & Tschöp, M. H. (2017). Gut-Brain Cross-Talk in Metabolic Control. Cell, 168(5), 758-774. https://doi.org/10.1016/j.cell.2017.01.025

Vancouver

Clemmensen C, Müller TD, Woods SC, Berthoud H-R, Seeley RJ, Tschöp MH. Gut-Brain Cross-Talk in Metabolic Control. Cell. 2017 feb. 23;168(5):758-774. https://doi.org/10.1016/j.cell.2017.01.025

Author

Clemmensen, Christoffer ; Müller, Timo D ; Woods, Stephen C ; Berthoud, Hans-Rudolf ; Seeley, Randy J ; Tschöp, Matthias H. / Gut-Brain Cross-Talk in Metabolic Control. I: Cell. 2017 ; Bind 168, Nr. 5. s. 758-774.

Bibtex

@article{157d68035e0744d5821d65746fdbac12,

title = "Gut-Brain Cross-Talk in Metabolic Control",

abstract = "Because human energy metabolism evolved to favor adiposity over leanness, the availability of palatable, easily attainable, and calorically dense foods has led to unprecedented levels of obesity and its associated metabolic co-morbidities that appear resistant to traditional lifestyle interventions. However, recent progress identifying the molecular signaling pathways through which the brain and the gastrointestinal system communicate to govern energy homeostasis, combined with emerging insights on the molecular mechanisms underlying successful bariatric surgery, gives reason to be optimistic that novel precision medicines that mimic, enhance, and/or modulate gut-brain signaling can have unprecedented potential for stopping the obesity and type 2 diabetes pandemics.",

keywords = "Animals, Appetite Regulation, Brain, Energy Metabolism, Gastrointestinal Tract, Homeostasis, Humans, Neural Pathways, Pleasure, Satiation, Journal Article, Review",

author = "Christoffer Clemmensen and M{\"u}ller, {Timo D} and Woods, {Stephen C} and Hans-Rudolf Berthoud and Seeley, {Randy J} and Tsch{\"o}p, {Matthias H}",

year = "2017",

month = feb,

day = "23",

doi = "10.1016/j.cell.2017.01.025",

language = "English",

volume = "168",

pages = "758--774",

journal = "Cell",

issn = "0092-8674",

publisher = "Cell Press",

number = "5",

}

RIS

TY - JOUR

T1 - Gut-Brain Cross-Talk in Metabolic Control

AU - Clemmensen, Christoffer

AU - Müller, Timo D

AU - Woods, Stephen C

AU - Berthoud, Hans-Rudolf

AU - Seeley, Randy J

AU - Tschöp, Matthias H

PY - 2017/2/23

Y1 - 2017/2/23

N2 - Because human energy metabolism evolved to favor adiposity over leanness, the availability of palatable, easily attainable, and calorically dense foods has led to unprecedented levels of obesity and its associated metabolic co-morbidities that appear resistant to traditional lifestyle interventions. However, recent progress identifying the molecular signaling pathways through which the brain and the gastrointestinal system communicate to govern energy homeostasis, combined with emerging insights on the molecular mechanisms underlying successful bariatric surgery, gives reason to be optimistic that novel precision medicines that mimic, enhance, and/or modulate gut-brain signaling can have unprecedented potential for stopping the obesity and type 2 diabetes pandemics.

AB - Because human energy metabolism evolved to favor adiposity over leanness, the availability of palatable, easily attainable, and calorically dense foods has led to unprecedented levels of obesity and its associated metabolic co-morbidities that appear resistant to traditional lifestyle interventions. However, recent progress identifying the molecular signaling pathways through which the brain and the gastrointestinal system communicate to govern energy homeostasis, combined with emerging insights on the molecular mechanisms underlying successful bariatric surgery, gives reason to be optimistic that novel precision medicines that mimic, enhance, and/or modulate gut-brain signaling can have unprecedented potential for stopping the obesity and type 2 diabetes pandemics.

KW - Animals

KW - Appetite Regulation

KW - Brain

KW - Energy Metabolism

KW - Gastrointestinal Tract

KW - Homeostasis

KW - Humans

KW - Neural Pathways

KW - Pleasure

KW - Satiation

KW - Journal Article

KW - Review

U2 - 10.1016/j.cell.2017.01.025

DO - 10.1016/j.cell.2017.01.025

M3 - Review

C2 - 28235194

VL - 168

SP - 758

EP - 774

JO - Cell

JF - Cell

SN - 0092-8674

IS - 5

ER -

ID: 186639734