Growth and differentiation factor 15 as a biomarker for mitochondrial myopathy

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

Growth and differentiation factor 15 as a biomarker for mitochondrial myopathy. / Poulsen, Nanna Scharff; Madsen, Karen Lindhardt; Hornsyld, Tessa Munkeboe; Eisum, Anne Sofie Vibæk; Fornander, Freja; Buch, Astrid Emilie; Stemmerik, Mads Godtfeldt; Ruiz-Ruiz, Cristina; Krag, Thomas Oliver; Vissing, John.

I: Mitochondrion, Bind 50, 01.2020, s. 35-41.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Poulsen, NS, Madsen, KL, Hornsyld, TM, Eisum, ASV, Fornander, F, Buch, AE, Stemmerik, MG, Ruiz-Ruiz, C, Krag, TO & Vissing, J 2020, 'Growth and differentiation factor 15 as a biomarker for mitochondrial myopathy', Mitochondrion, bind 50, s. 35-41. https://doi.org/10.1016/j.mito.2019.10.005

APA

Poulsen, N. S., Madsen, K. L., Hornsyld, T. M., Eisum, A. S. V., Fornander, F., Buch, A. E., Stemmerik, M. G., Ruiz-Ruiz, C., Krag, T. O., & Vissing, J. (2020). Growth and differentiation factor 15 as a biomarker for mitochondrial myopathy. Mitochondrion, 50, 35-41. https://doi.org/10.1016/j.mito.2019.10.005

Vancouver

Poulsen NS, Madsen KL, Hornsyld TM, Eisum ASV, Fornander F, Buch AE o.a. Growth and differentiation factor 15 as a biomarker for mitochondrial myopathy. Mitochondrion. 2020 jan.;50:35-41. https://doi.org/10.1016/j.mito.2019.10.005

Author

Poulsen, Nanna Scharff ; Madsen, Karen Lindhardt ; Hornsyld, Tessa Munkeboe ; Eisum, Anne Sofie Vibæk ; Fornander, Freja ; Buch, Astrid Emilie ; Stemmerik, Mads Godtfeldt ; Ruiz-Ruiz, Cristina ; Krag, Thomas Oliver ; Vissing, John. / Growth and differentiation factor 15 as a biomarker for mitochondrial myopathy. I: Mitochondrion. 2020 ; Bind 50. s. 35-41.

Bibtex

@article{179808f94d074406ba66ae72908bf632,
title = "Growth and differentiation factor 15 as a biomarker for mitochondrial myopathy",
abstract = "Objective: We investigated if Growth and Differentiation Factor 15 (GDF-15) can be used as a biomarker to distinguish patients with mitochondrial myopathy from patients with other myopathies. Methods: Serum GDF-15 was measured in 28 patients with mitochondrial disease, 24 with metabolic myopathies, 27 with muscular dystrophy and 21 healthy controls. Results and conclusions: Our findings indicate that elevated GDF-15 can distinguish patients with mitochondrial myopathy from other myopathies, including metabolic myopathies. This suggests that increases in GDF-15 is specific to respiratory chain dysfunction rather than general metabolic dysfunction or muscle defect.",
keywords = "Exercise, Growth and differentiation factor 15, Metabolic myopathy, Mitochondrial myopathy, Muscular dystrophy",
author = "Poulsen, {Nanna Scharff} and Madsen, {Karen Lindhardt} and Hornsyld, {Tessa Munkeboe} and Eisum, {Anne Sofie Vib{\ae}k} and Freja Fornander and Buch, {Astrid Emilie} and Stemmerik, {Mads Godtfeldt} and Cristina Ruiz-Ruiz and Krag, {Thomas Oliver} and John Vissing",
year = "2020",
month = jan,
doi = "10.1016/j.mito.2019.10.005",
language = "English",
volume = "50",
pages = "35--41",
journal = "Mitochondrion",
issn = "1567-7249",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Growth and differentiation factor 15 as a biomarker for mitochondrial myopathy

AU - Poulsen, Nanna Scharff

AU - Madsen, Karen Lindhardt

AU - Hornsyld, Tessa Munkeboe

AU - Eisum, Anne Sofie Vibæk

AU - Fornander, Freja

AU - Buch, Astrid Emilie

AU - Stemmerik, Mads Godtfeldt

AU - Ruiz-Ruiz, Cristina

AU - Krag, Thomas Oliver

AU - Vissing, John

PY - 2020/1

Y1 - 2020/1

N2 - Objective: We investigated if Growth and Differentiation Factor 15 (GDF-15) can be used as a biomarker to distinguish patients with mitochondrial myopathy from patients with other myopathies. Methods: Serum GDF-15 was measured in 28 patients with mitochondrial disease, 24 with metabolic myopathies, 27 with muscular dystrophy and 21 healthy controls. Results and conclusions: Our findings indicate that elevated GDF-15 can distinguish patients with mitochondrial myopathy from other myopathies, including metabolic myopathies. This suggests that increases in GDF-15 is specific to respiratory chain dysfunction rather than general metabolic dysfunction or muscle defect.

AB - Objective: We investigated if Growth and Differentiation Factor 15 (GDF-15) can be used as a biomarker to distinguish patients with mitochondrial myopathy from patients with other myopathies. Methods: Serum GDF-15 was measured in 28 patients with mitochondrial disease, 24 with metabolic myopathies, 27 with muscular dystrophy and 21 healthy controls. Results and conclusions: Our findings indicate that elevated GDF-15 can distinguish patients with mitochondrial myopathy from other myopathies, including metabolic myopathies. This suggests that increases in GDF-15 is specific to respiratory chain dysfunction rather than general metabolic dysfunction or muscle defect.

KW - Exercise

KW - Growth and differentiation factor 15

KW - Metabolic myopathy

KW - Mitochondrial myopathy

KW - Muscular dystrophy

UR - http://www.scopus.com/inward/record.url?scp=85074229656&partnerID=8YFLogxK

U2 - 10.1016/j.mito.2019.10.005

DO - 10.1016/j.mito.2019.10.005

M3 - Journal article

C2 - 31669236

AN - SCOPUS:85074229656

VL - 50

SP - 35

EP - 41

JO - Mitochondrion

JF - Mitochondrion

SN - 1567-7249

ER -

ID: 240243210