Good health-related quality-of-life and high patient-reported satisfaction after delayed breast reconstruction with pedicled flaps from the back
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Good health-related quality-of-life and high patient-reported satisfaction after delayed breast reconstruction with pedicled flaps from the back. / Rindom, Mikkel Børsen; Gunnarsson, Gudjon L.; Lautrup, Marianne D.; Tos, Tina; Hölmich, Professor Lisbet R.; Sørensen, Professor Jens A.; Thomsen, Jørn B.
I: Journal of Plastic, Reconstructive and Aesthetic Surgery, Bind 74, Nr. 8, 2021, s. 1752-1757.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Good health-related quality-of-life and high patient-reported satisfaction after delayed breast reconstruction with pedicled flaps from the back
AU - Rindom, Mikkel Børsen
AU - Gunnarsson, Gudjon L.
AU - Lautrup, Marianne D.
AU - Tos, Tina
AU - Hölmich, Professor Lisbet R.
AU - Sørensen, Professor Jens A.
AU - Thomsen, Jørn B.
N1 - Publisher Copyright: © 2020
PY - 2021
Y1 - 2021
N2 - Background: This paper presents the results of a randomized controlled trial (RCT) that focus on health-related quality-of-life (QoL) and patient-reported satisfaction following breast reconstruction with pedicled flaps from the back. Materials & Methods: We included women for unilateral delayed breast reconstruction. Patients were randomized to reconstruction by either a latissimus dorsi (LD) flap or a thoracodorsal artery perforator (TAP) flap. Assessment of QoL and patient satisfaction was made using two different patient-reported outcome measures (PROMs): The EORTC QLQ-30 and the Breast-Q questionnaire for post-mastectomy breast reconstruction. Results: A total of 50 women were enrolled over a two-year period and allocated to reconstruction. Forty patients completed both surgery and follow-up and were included in the analysis – 18 in the LD group and 22 in the TAP group. The EORTC QLQ-30 was administered at the baseline and at one-year follow-up. There was no significant effect of introducing the TAP flap on either the summary score, the global QoL-score or the financial impact-score when compared to the LD flap. The Breast-Q questionnaire was administered only at one-year follow-up. There was no significant difference between the two groups for the scores for satisfaction with the reconstructed breast, the overall outcome and QoL related to psycho-social, sexual and physical well-being. Conclusion: Women from both groups report high satisfaction and QoL following the reconstruction. The quality of the dataset and the study design are, however, insufficient to rule out any existing difference. A larger cohort, longer follow-up and different design are warranted to assess the true clinical significance these reconstructions might have on satisfaction and QoL.
AB - Background: This paper presents the results of a randomized controlled trial (RCT) that focus on health-related quality-of-life (QoL) and patient-reported satisfaction following breast reconstruction with pedicled flaps from the back. Materials & Methods: We included women for unilateral delayed breast reconstruction. Patients were randomized to reconstruction by either a latissimus dorsi (LD) flap or a thoracodorsal artery perforator (TAP) flap. Assessment of QoL and patient satisfaction was made using two different patient-reported outcome measures (PROMs): The EORTC QLQ-30 and the Breast-Q questionnaire for post-mastectomy breast reconstruction. Results: A total of 50 women were enrolled over a two-year period and allocated to reconstruction. Forty patients completed both surgery and follow-up and were included in the analysis – 18 in the LD group and 22 in the TAP group. The EORTC QLQ-30 was administered at the baseline and at one-year follow-up. There was no significant effect of introducing the TAP flap on either the summary score, the global QoL-score or the financial impact-score when compared to the LD flap. The Breast-Q questionnaire was administered only at one-year follow-up. There was no significant difference between the two groups for the scores for satisfaction with the reconstructed breast, the overall outcome and QoL related to psycho-social, sexual and physical well-being. Conclusion: Women from both groups report high satisfaction and QoL following the reconstruction. The quality of the dataset and the study design are, however, insufficient to rule out any existing difference. A larger cohort, longer follow-up and different design are warranted to assess the true clinical significance these reconstructions might have on satisfaction and QoL.
KW - Breast reconstruction
KW - Breast-Q
KW - EORTC QLQ-30
KW - Latissimus dorsi flap
KW - Patient-reported outcome
KW - Thoracodorsal artery perforator flap
U2 - 10.1016/j.bjps.2020.12.019
DO - 10.1016/j.bjps.2020.12.019
M3 - Journal article
C2 - 33676866
AN - SCOPUS:85102064224
VL - 74
SP - 1752
EP - 1757
JO - Journal of plastic, reconstructive & aesthetic surgery : JPRAS
JF - Journal of plastic, reconstructive & aesthetic surgery : JPRAS
SN - 1748-6815
IS - 8
ER -
ID: 301357289