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Genome-wide association study of prostate cancer-specific survival. / Szulkin, Robert; Karlsson, Robert; Whitington, Thomas; Aly, Markus; Gronberg, Henrik; Eeles, Rosalind A; Easton, Douglas F; Kote-Jarai, Zsofia; Al Olama, Ali Amin; Benlloch, Sara; Muir, Kenneth; Giles, Graham G; Southey, Melissa C; FitzGerald, Liesel M; Henderson, Brian E; Schumacher, Fredrick R; Haiman, Christopher A; Sipeky, Csilla; Tammela, Teuvo L J; Nordestgaard, Børge G; Key, Timothy J; Travis, Ruth C; Neal, David E; Donovan, Jenny L; Hamdy, Freddie C; Pharoah, Paul D P; Pashayan, Nora; Khaw, Kay-Tee; Stanford, Janet L; Thibodeau, Stephen N; McDonnell, Shannon K; Schaid, Daniel J; Maier, Christiane; Vogel, Walther; Luedeke, Manuel; Herkommer, Kathleen; Kibel, Adam S; Cybulski, Cezary; Lubiński, Jan; Kluźniak, Wojciech; Cannon-Albright, Lisa; Brenner, Hermann; Herrmann, Volker; Holleczek, Bernd; Park, Jong Y; Sellers, Thomas A; Lim, Hui-Yi; Slavov, Chavdar; Kaneva, Radka P; Mitev, Vanio I; PRACTICAL consortium.
I:
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Bind 24, Nr. 11, 11.2015, s. 1796-1800.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
Szulkin, R, Karlsson, R, Whitington, T, Aly, M, Gronberg, H, Eeles, RA, Easton, DF, Kote-Jarai, Z, Al Olama, AA, Benlloch, S, Muir, K, Giles, GG, Southey, MC, FitzGerald, LM, Henderson, BE, Schumacher, FR, Haiman, CA, Sipeky, C, Tammela, TLJ
, Nordestgaard, BG, Key, TJ, Travis, RC, Neal, DE, Donovan, JL, Hamdy, FC, Pharoah, PDP, Pashayan, N, Khaw, K-T, Stanford, JL, Thibodeau, SN, McDonnell, SK, Schaid, DJ, Maier, C, Vogel, W, Luedeke, M, Herkommer, K, Kibel, AS, Cybulski, C, Lubiński, J, Kluźniak, W, Cannon-Albright, L, Brenner, H, Herrmann, V, Holleczek, B, Park, JY, Sellers, TA, Lim, H-Y, Slavov, C, Kaneva, RP, Mitev, VI & PRACTICAL consortium 2015, '
Genome-wide association study of prostate cancer-specific survival',
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, bind 24, nr. 11, s. 1796-1800.
https://doi.org/10.1158/1055-9965.EPI-15-0543
APA
Szulkin, R., Karlsson, R., Whitington, T., Aly, M., Gronberg, H., Eeles, R. A., Easton, D. F., Kote-Jarai, Z., Al Olama, A. A., Benlloch, S., Muir, K., Giles, G. G., Southey, M. C., FitzGerald, L. M., Henderson, B. E., Schumacher, F. R., Haiman, C. A., Sipeky, C., Tammela, T. L. J., ... PRACTICAL consortium (2015).
Genome-wide association study of prostate cancer-specific survival.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology,
24(11), 1796-1800.
https://doi.org/10.1158/1055-9965.EPI-15-0543
Vancouver
Szulkin R, Karlsson R, Whitington T, Aly M, Gronberg H, Eeles RA o.a.
Genome-wide association study of prostate cancer-specific survival.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2015 nov.;24(11):1796-1800.
https://doi.org/10.1158/1055-9965.EPI-15-0543
Author
Szulkin, Robert ; Karlsson, Robert ; Whitington, Thomas ; Aly, Markus ; Gronberg, Henrik ; Eeles, Rosalind A ; Easton, Douglas F ; Kote-Jarai, Zsofia ; Al Olama, Ali Amin ; Benlloch, Sara ; Muir, Kenneth ; Giles, Graham G ; Southey, Melissa C ; FitzGerald, Liesel M ; Henderson, Brian E ; Schumacher, Fredrick R ; Haiman, Christopher A ; Sipeky, Csilla ; Tammela, Teuvo L J ; Nordestgaard, Børge G ; Key, Timothy J ; Travis, Ruth C ; Neal, David E ; Donovan, Jenny L ; Hamdy, Freddie C ; Pharoah, Paul D P ; Pashayan, Nora ; Khaw, Kay-Tee ; Stanford, Janet L ; Thibodeau, Stephen N ; McDonnell, Shannon K ; Schaid, Daniel J ; Maier, Christiane ; Vogel, Walther ; Luedeke, Manuel ; Herkommer, Kathleen ; Kibel, Adam S ; Cybulski, Cezary ; Lubiński, Jan ; Kluźniak, Wojciech ; Cannon-Albright, Lisa ; Brenner, Hermann ; Herrmann, Volker ; Holleczek, Bernd ; Park, Jong Y ; Sellers, Thomas A ; Lim, Hui-Yi ; Slavov, Chavdar ; Kaneva, Radka P ; Mitev, Vanio I ; PRACTICAL consortium. / Genome-wide association study of prostate cancer-specific survival. I: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2015 ; Bind 24, Nr. 11. s. 1796-1800.
Bibtex
@article{b2e8953472574c4a84ed8fd5430d94b1,
title = "Genome-wide association study of prostate cancer-specific survival",
abstract = "BACKGROUND: Unnecessary intervention and overtreatment of indolent disease are common challenges in clinical management of prostate cancer. Improved tools to distinguish lethal from indolent disease are critical.METHODS: We performed a genome-wide survival analysis of cause-specific death in 24,023 prostate cancer patients (3,513 disease-specific deaths) from the PRACTICAL and BPC3 consortia. Top findings were assessed for replication in a Norwegian cohort (CONOR).RESULTS: We observed no significant association between genetic variants and prostate cancer survival.CONCLUSIONS: Common genetic variants with large impact on prostate cancer survival were not observed in this study.IMPACT: Future studies should be designed for identification of rare variants with large effect sizes or common variants with small effect sizes.",
author = "Robert Szulkin and Robert Karlsson and Thomas Whitington and Markus Aly and Henrik Gronberg and Eeles, {Rosalind A} and Easton, {Douglas F} and Zsofia Kote-Jarai and {Al Olama}, {Ali Amin} and Sara Benlloch and Kenneth Muir and Giles, {Graham G} and Southey, {Melissa C} and FitzGerald, {Liesel M} and Henderson, {Brian E} and Schumacher, {Fredrick R} and Haiman, {Christopher A} and Csilla Sipeky and Tammela, {Teuvo L J} and Nordestgaard, {B{\o}rge G} and Key, {Timothy J} and Travis, {Ruth C} and Neal, {David E} and Donovan, {Jenny L} and Hamdy, {Freddie C} and Pharoah, {Paul D P} and Nora Pashayan and Kay-Tee Khaw and Stanford, {Janet L} and Thibodeau, {Stephen N} and McDonnell, {Shannon K} and Schaid, {Daniel J} and Christiane Maier and Walther Vogel and Manuel Luedeke and Kathleen Herkommer and Kibel, {Adam S} and Cezary Cybulski and Jan Lubi{\'n}ski and Wojciech Klu{\'z}niak and Lisa Cannon-Albright and Hermann Brenner and Volker Herrmann and Bernd Holleczek and Park, {Jong Y} and Sellers, {Thomas A} and Hui-Yi Lim and Chavdar Slavov and Kaneva, {Radka P} and Mitev, {Vanio I} and {PRACTICAL consortium}",
note = "{\textcopyright}2015 American Association for Cancer Research.",
year = "2015",
month = nov,
doi = "10.1158/1055-9965.EPI-15-0543",
language = "English",
volume = "24",
pages = "1796--1800",
journal = "Cancer Epidemiology, Biomarkers & Prevention",
issn = "1055-9965",
publisher = "American Association for Cancer Research (A A C R)",
number = "11",
}
RIS
TY - JOUR
T1 - Genome-wide association study of prostate cancer-specific survival
AU - Szulkin, Robert
AU - Karlsson, Robert
AU - Whitington, Thomas
AU - Aly, Markus
AU - Gronberg, Henrik
AU - Eeles, Rosalind A
AU - Easton, Douglas F
AU - Kote-Jarai, Zsofia
AU - Al Olama, Ali Amin
AU - Benlloch, Sara
AU - Muir, Kenneth
AU - Giles, Graham G
AU - Southey, Melissa C
AU - FitzGerald, Liesel M
AU - Henderson, Brian E
AU - Schumacher, Fredrick R
AU - Haiman, Christopher A
AU - Sipeky, Csilla
AU - Tammela, Teuvo L J
AU - Nordestgaard, Børge G
AU - Key, Timothy J
AU - Travis, Ruth C
AU - Neal, David E
AU - Donovan, Jenny L
AU - Hamdy, Freddie C
AU - Pharoah, Paul D P
AU - Pashayan, Nora
AU - Khaw, Kay-Tee
AU - Stanford, Janet L
AU - Thibodeau, Stephen N
AU - McDonnell, Shannon K
AU - Schaid, Daniel J
AU - Maier, Christiane
AU - Vogel, Walther
AU - Luedeke, Manuel
AU - Herkommer, Kathleen
AU - Kibel, Adam S
AU - Cybulski, Cezary
AU - Lubiński, Jan
AU - Kluźniak, Wojciech
AU - Cannon-Albright, Lisa
AU - Brenner, Hermann
AU - Herrmann, Volker
AU - Holleczek, Bernd
AU - Park, Jong Y
AU - Sellers, Thomas A
AU - Lim, Hui-Yi
AU - Slavov, Chavdar
AU - Kaneva, Radka P
AU - Mitev, Vanio I
AU - PRACTICAL consortium
N1 - ©2015 American Association for Cancer Research.
PY - 2015/11
Y1 - 2015/11
N2 - BACKGROUND: Unnecessary intervention and overtreatment of indolent disease are common challenges in clinical management of prostate cancer. Improved tools to distinguish lethal from indolent disease are critical.METHODS: We performed a genome-wide survival analysis of cause-specific death in 24,023 prostate cancer patients (3,513 disease-specific deaths) from the PRACTICAL and BPC3 consortia. Top findings were assessed for replication in a Norwegian cohort (CONOR).RESULTS: We observed no significant association between genetic variants and prostate cancer survival.CONCLUSIONS: Common genetic variants with large impact on prostate cancer survival were not observed in this study.IMPACT: Future studies should be designed for identification of rare variants with large effect sizes or common variants with small effect sizes.
AB - BACKGROUND: Unnecessary intervention and overtreatment of indolent disease are common challenges in clinical management of prostate cancer. Improved tools to distinguish lethal from indolent disease are critical.METHODS: We performed a genome-wide survival analysis of cause-specific death in 24,023 prostate cancer patients (3,513 disease-specific deaths) from the PRACTICAL and BPC3 consortia. Top findings were assessed for replication in a Norwegian cohort (CONOR).RESULTS: We observed no significant association between genetic variants and prostate cancer survival.CONCLUSIONS: Common genetic variants with large impact on prostate cancer survival were not observed in this study.IMPACT: Future studies should be designed for identification of rare variants with large effect sizes or common variants with small effect sizes.
U2 - 10.1158/1055-9965.EPI-15-0543
DO - 10.1158/1055-9965.EPI-15-0543
M3 - Journal article
C2 - 26307654
VL - 24
SP - 1796
EP - 1800
JO - Cancer Epidemiology, Biomarkers & Prevention
JF - Cancer Epidemiology, Biomarkers & Prevention
SN - 1055-9965
IS - 11
ER -