Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

  • Matthew Traylor
  • Martin Farrall
  • Elizabeth G Holliday
  • Cathie Sudlow
  • Jemma C Hopewell
  • Yu-Ching Cheng
  • Myriam Fornage
  • M Arfan Ikram
  • Rainer Malik
  • Steve Bevan
  • Unnur Thorsteinsdottir
  • Mike A Nalls
  • Wt Longstreth
  • Kerri L Wiggins
  • Sunaina Yadav
  • Eugenio A Parati
  • Anita L Destefano
  • Bradford B Worrall
  • Steven J Kittner
  • Muhammad Saleem Khan
  • Alex P Reiner
  • Anna Helgadottir
  • Sefanja Achterberg
  • Israel Fernandez-Cadenas
  • Sherine Abboud
  • Reinhold Schmidt
  • Matthew Walters
  • Wei-Min Chen
  • E Bernd Ringelstein
  • Martin O'Donnell
  • Weang Kee Ho
  • Joanna Pera
  • Robin Lemmens
  • Bo Norrving
  • Peter Higgins
  • Marianne Benn
  • Michele Sale
  • Gregor Kuhlenbäumer
  • Alexander S F Doney
  • Astrid M Vicente
  • Hossein Delavaran
  • Ale Algra
  • Gail Davies
  • Sofia A Oliveira
  • Colin N A Palmer
  • Ian Deary
  • Helena Schmidt
  • Massimo Pandolfo
  • Joan Montaner
  • Nordestgaard, Børge
  • Australian Stroke Genetics Collaborative, Wellcome Trust Case Control Consortium 2 (WTCCC2)
Various genome-wide association studies (GWAS) have been done in ischaemic stroke, identifying a few loci associated with the disease, but sample sizes have been 3500 cases or less. We established the METASTROKE collaboration with the aim of validating associations from previous GWAS and identifying novel genetic associations through meta-analysis of GWAS datasets for ischaemic stroke and its subtypes.
OriginalsprogEngelsk
TidsskriftLancet Neurology
Vol/bind11
Udgave nummer11
Sider (fra-til)951-62
Antal sider12
ISSN1474-4422
DOI
StatusUdgivet - 2012

ID: 48540979