Flexural eczema versus atopic dermatitis
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Flexural eczema versus atopic dermatitis. / Jacob, Sharon E; Goldenberg, Alina; Nedorost, Susan; Thyssen, Jacob P; Fonacier, Luz; Spiewak, Radoslaw.
I: Dermatitis, Bind 26, Nr. 3, 20.05.2015, s. 109-15.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Flexural eczema versus atopic dermatitis
AU - Jacob, Sharon E
AU - Goldenberg, Alina
AU - Nedorost, Susan
AU - Thyssen, Jacob P
AU - Fonacier, Luz
AU - Spiewak, Radoslaw
PY - 2015/5/20
Y1 - 2015/5/20
N2 - Flexural eczema and atopic dermatitis are frequently synonymized. As respiratory atopy is rarely tested for and found in these patients, systematically equating a flexural distribution of dermatitis with atopic dermatitis may too frequently result in misclassified diagnoses and potentially missed opportunity for intervention toward improving patients' symptoms and quality of life. We present a critical review of the available evidence for the atopic dermatitis diagnosis and discuss the similarities between atopic dermatitis and allergic contact dermatitis. Because neither flexural predilection nor atopy is specific for atopic dermatitis, we conclude that the term atopic dermatitis is a misnomer and propose an etymologic reclassification of atopic dermatitis to "atopy-related" dermatitis. Allergic contact dermatitis can induce an atopic dermatitis-like phenotype, and thus, flexural dermatitis cannot be assumed as atopic without further testing. Patch testing should at least be considered in cases of chronic or recurrent eczema regardless of the working diagnosis.
AB - Flexural eczema and atopic dermatitis are frequently synonymized. As respiratory atopy is rarely tested for and found in these patients, systematically equating a flexural distribution of dermatitis with atopic dermatitis may too frequently result in misclassified diagnoses and potentially missed opportunity for intervention toward improving patients' symptoms and quality of life. We present a critical review of the available evidence for the atopic dermatitis diagnosis and discuss the similarities between atopic dermatitis and allergic contact dermatitis. Because neither flexural predilection nor atopy is specific for atopic dermatitis, we conclude that the term atopic dermatitis is a misnomer and propose an etymologic reclassification of atopic dermatitis to "atopy-related" dermatitis. Allergic contact dermatitis can induce an atopic dermatitis-like phenotype, and thus, flexural dermatitis cannot be assumed as atopic without further testing. Patch testing should at least be considered in cases of chronic or recurrent eczema regardless of the working diagnosis.
KW - Ankle
KW - Dermatitis, Allergic Contact
KW - Dermatitis, Atopic
KW - Eczema
KW - Elbow
KW - Humans
KW - Knee
KW - Neck
U2 - 10.1097/DER.0000000000000102
DO - 10.1097/DER.0000000000000102
M3 - Journal article
C2 - 25984686
VL - 26
SP - 109
EP - 115
JO - Dermatitis
JF - Dermatitis
SN - 1710-3568
IS - 3
ER -
ID: 162155326