First come, first served: Mammalian recombination is timed to replication
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Meiotic recombination drives the formation of new chromosomes in germ cells and is essential for fertility in mammals. In this issue of Cell, Pratto et al. have developed a method to map replication origins directly in mammalian tissue for the first time, revealing evolutionary conservation between replication timing and meiotic recombination in males.
Originalsprog | Engelsk |
---|---|
Tidsskrift | Cell |
Vol/bind | 184 |
Udgave nummer | 16 |
Sider (fra-til) | 4112-4114 |
Antal sider | 3 |
ISSN | 0092-8674 |
DOI | |
Status | Udgivet - 2021 |
Bibliografisk note
Funding Information:
J.A.H. is funded by a postdoctoral fellowship award by the Lundbeck Foundation ( R347-2020-2177 ). Research in the E.R.H. lab is funded by the ERC ( 724718-ReCAP ), Novo Nordisk Foundation ( NNF15COC0016662 ), and Danish National Research Foundation Center ( 6110-00344B ).
Publisher Copyright:
© 2021
ID: 276271009