Fast Super Resolution Ultrasound Imaging using the Erythrocytes
Publikation: Bidrag til bog/antologi/rapport › Konferencebidrag i proceedings › Forskning › fagfællebedømt
Standard
Fast Super Resolution Ultrasound Imaging using the Erythrocytes. / Jensen, Jorgen Arendt; Schou, Mikkel; Andersen, Sofie Bech; Sogaard, Stinne Byrholdt; Sorensen, Charlotte Mehlin; Nielsen, Michael Bachmann; Gundlach, Carsten; Kjer, Hans Martin; Dahl, Anders Bjorholm; Stuart, Matthias Bo; Tomov, Borislav Gueorguiev.
Medical Imaging 2022: Ultrasonic Imaging and Tomography. red. / Nick Bottenus; Nicole V. Ruiter. SPIE, 2022. s. 1-7 120380E (Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Bind 12038).Publikation: Bidrag til bog/antologi/rapport › Konferencebidrag i proceedings › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - GEN
T1 - Fast Super Resolution Ultrasound Imaging using the Erythrocytes
AU - Jensen, Jorgen Arendt
AU - Schou, Mikkel
AU - Andersen, Sofie Bech
AU - Sogaard, Stinne Byrholdt
AU - Sorensen, Charlotte Mehlin
AU - Nielsen, Michael Bachmann
AU - Gundlach, Carsten
AU - Kjer, Hans Martin
AU - Dahl, Anders Bjorholm
AU - Stuart, Matthias Bo
AU - Tomov, Borislav Gueorguiev
N1 - Publisher Copyright: © 2022 SPIE. All rights reserved.
PY - 2022
Y1 - 2022
N2 - Super resolution (SR) imaging is currently conducted using fragile ultrasound contrast agents. This precludes using the full acoustic pressure range, and the distribution of bubbles has to be sparse for them to be isolated for SR imaging. Images have to be acquired over minutes to accumulate enough positions for visualizing the vas- culature. A new method for SUper Resolution imaging using the Erythrocytes (SURE) as targets is introduced, which makes it possible to maximize the emitted pressure for good signal-to-noise ratios. The abundant number of erythrocyte targets make acquisition fast, and the SURE images can be acquired in seconds. A Verasonics Vantage 256 scanner was used in combination with a GE L8-18iD linear array probe operated at 10 MHz for a wavelength of 150 m. A 12 emissions synthetic aperture ultrasound sequence was employed to scan the kidney of a Sprague-Dawley rat for 24 seconds to visualize its vasculature. An ex vivo micro-CT image using the contrast agent Microfil was also acquired at a voxel size of 22.6 m for validating the SURE images. The SURE image revealed vessels with a size down to 29 fim, five times smaller than the ultrasound wavelength, and the dense grid of vessels in the full kidney was reliably shown for scan times between 1 to 24 seconds. Visually the SURE images revealed the same vasculature as the micro-CT images. SURE images are acquired in seconds rather than minutes without contrast injection for easy clinical use, and they can be measured at full regulatory levels for pressure, intensity, and probe temperature.
AB - Super resolution (SR) imaging is currently conducted using fragile ultrasound contrast agents. This precludes using the full acoustic pressure range, and the distribution of bubbles has to be sparse for them to be isolated for SR imaging. Images have to be acquired over minutes to accumulate enough positions for visualizing the vas- culature. A new method for SUper Resolution imaging using the Erythrocytes (SURE) as targets is introduced, which makes it possible to maximize the emitted pressure for good signal-to-noise ratios. The abundant number of erythrocyte targets make acquisition fast, and the SURE images can be acquired in seconds. A Verasonics Vantage 256 scanner was used in combination with a GE L8-18iD linear array probe operated at 10 MHz for a wavelength of 150 m. A 12 emissions synthetic aperture ultrasound sequence was employed to scan the kidney of a Sprague-Dawley rat for 24 seconds to visualize its vasculature. An ex vivo micro-CT image using the contrast agent Microfil was also acquired at a voxel size of 22.6 m for validating the SURE images. The SURE image revealed vessels with a size down to 29 fim, five times smaller than the ultrasound wavelength, and the dense grid of vessels in the full kidney was reliably shown for scan times between 1 to 24 seconds. Visually the SURE images revealed the same vasculature as the micro-CT images. SURE images are acquired in seconds rather than minutes without contrast injection for easy clinical use, and they can be measured at full regulatory levels for pressure, intensity, and probe temperature.
UR - http://www.scopus.com/inward/record.url?scp=85132027562&partnerID=8YFLogxK
U2 - 10.1117/12.2612245
DO - 10.1117/12.2612245
M3 - Article in proceedings
AN - SCOPUS:85132027562
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
SP - 1
EP - 7
BT - Medical Imaging 2022
A2 - Bottenus, Nick
A2 - Ruiter, Nicole V.
PB - SPIE
T2 - Medical Imaging 2022: Ultrasonic Imaging and Tomography
Y2 - 21 March 2022 through 27 March 2022
ER -
ID: 313709327