Fact, overdiagnosis cannot be evaluated by comparing histological grading of prostate biopsy to prostatectomy specimen
Publikation: Bidrag til tidsskrift › Letter › Forskning › fagfællebedømt
Standard
Fact, overdiagnosis cannot be evaluated by comparing histological grading of prostate biopsy to prostatectomy specimen. / Stroomberg, Hein Vincent; Brasso, Klaus; Røder, Andreas.
I: Prostate Cancer and Prostatic Diseases, 2023, s. 804–805.Publikation: Bidrag til tidsskrift › Letter › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Fact, overdiagnosis cannot be evaluated by comparing histological grading of prostate biopsy to prostatectomy specimen
AU - Stroomberg, Hein Vincent
AU - Brasso, Klaus
AU - Røder, Andreas
PY - 2023
Y1 - 2023
N2 - The authors show that ISUP 2 histological grade obtained by multiparametric MRI biopsies targeted to the cancerous lesion is seldomly downgraded when compared with the RP specimen and suggest that MRI targeting does not lead to overdiagnosis [1]. Overdiagnosis is a term used to describe men who are diagnosed with a disease that will never develop into symptoms or death, which is not reported here. Moreover, some aspects of the article need of clarification. The authors state that the men included had no prior biopsies, however, in the Table, 210 men are reported with one or more prior biopsies. Furthermore, among the men with ISUP 2 on RP pathology, 60% is reported as pT0, indicating no cancer found in the specimen, and an additional 32% is reported with pT1, both findings need clarification.
AB - The authors show that ISUP 2 histological grade obtained by multiparametric MRI biopsies targeted to the cancerous lesion is seldomly downgraded when compared with the RP specimen and suggest that MRI targeting does not lead to overdiagnosis [1]. Overdiagnosis is a term used to describe men who are diagnosed with a disease that will never develop into symptoms or death, which is not reported here. Moreover, some aspects of the article need of clarification. The authors state that the men included had no prior biopsies, however, in the Table, 210 men are reported with one or more prior biopsies. Furthermore, among the men with ISUP 2 on RP pathology, 60% is reported as pT0, indicating no cancer found in the specimen, and an additional 32% is reported with pT1, both findings need clarification.
U2 - 10.1038/s41391-022-00629-z
DO - 10.1038/s41391-022-00629-z
M3 - Letter
C2 - 36494606
AN - SCOPUS:85143609015
SP - 804
EP - 805
JO - Prostate Cancer and Prostatic Diseases
JF - Prostate Cancer and Prostatic Diseases
SN - 1365-7852
ER -
ID: 330521985