Evaluation of a neurodevelopmental model of schizophrenia--early postnatal PCP treatment in attentional set-shifting

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

Evaluation of a neurodevelopmental model of schizophrenia--early postnatal PCP treatment in attentional set-shifting. / Broberg, Brian Villumsen; Dias, Rebecca; Glenthøj, Birte Yding; Olsen, Christina Kurre.

I: Behavioural Brain Research, Bind 190, Nr. 1, 2008, s. 160-3.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Broberg, BV, Dias, R, Glenthøj, BY & Olsen, CK 2008, 'Evaluation of a neurodevelopmental model of schizophrenia--early postnatal PCP treatment in attentional set-shifting', Behavioural Brain Research, bind 190, nr. 1, s. 160-3. https://doi.org/10.1016/j.bbr.2008.02.020

APA

Broberg, B. V., Dias, R., Glenthøj, B. Y., & Olsen, C. K. (2008). Evaluation of a neurodevelopmental model of schizophrenia--early postnatal PCP treatment in attentional set-shifting. Behavioural Brain Research, 190(1), 160-3. https://doi.org/10.1016/j.bbr.2008.02.020

Vancouver

Broberg BV, Dias R, Glenthøj BY, Olsen CK. Evaluation of a neurodevelopmental model of schizophrenia--early postnatal PCP treatment in attentional set-shifting. Behavioural Brain Research. 2008;190(1):160-3. https://doi.org/10.1016/j.bbr.2008.02.020

Author

Broberg, Brian Villumsen ; Dias, Rebecca ; Glenthøj, Birte Yding ; Olsen, Christina Kurre. / Evaluation of a neurodevelopmental model of schizophrenia--early postnatal PCP treatment in attentional set-shifting. I: Behavioural Brain Research. 2008 ; Bind 190, Nr. 1. s. 160-3.

Bibtex

@article{e9b850fcdb2a456cbfbd1f4340d175fb,
title = "Evaluation of a neurodevelopmental model of schizophrenia--early postnatal PCP treatment in attentional set-shifting",
abstract = "Phencyclidine (PCP) was administered to male and female Lister hooded rats on postnatal days (PND) 7, 9 and 11. All PCP animals tested in adulthood (PND 53-93) showed deficits in cognitive flexibility, specifically in their ability to shift attentional set, compared to controls. This novel finding is reminiscent of the impairment observed in schizophrenia patients, and supports the validity of the early postnatal PCP regimen as a disease-like model.",
author = "Broberg, {Brian Villumsen} and Rebecca Dias and Glenth{\o}j, {Birte Yding} and Olsen, {Christina Kurre}",
note = "Keywords: Age Factors; Animals; Animals, Newborn; Attention; Behavior, Animal; Discrimination (Psychology); Disease Models, Animal; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Female; Male; Odors; Phencyclidine; Pregnancy; Rats; Schizophrenia; Sex Factors",
year = "2008",
doi = "http://dx.doi.org/10.1016/j.bbr.2008.02.020",
language = "English",
volume = "190",
pages = "160--3",
journal = "Behavioural Brain Research",
issn = "0166-4328",
publisher = "Elsevier",
number = "1",

}

RIS

TY - JOUR

T1 - Evaluation of a neurodevelopmental model of schizophrenia--early postnatal PCP treatment in attentional set-shifting

AU - Broberg, Brian Villumsen

AU - Dias, Rebecca

AU - Glenthøj, Birte Yding

AU - Olsen, Christina Kurre

N1 - Keywords: Age Factors; Animals; Animals, Newborn; Attention; Behavior, Animal; Discrimination (Psychology); Disease Models, Animal; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Female; Male; Odors; Phencyclidine; Pregnancy; Rats; Schizophrenia; Sex Factors

PY - 2008

Y1 - 2008

N2 - Phencyclidine (PCP) was administered to male and female Lister hooded rats on postnatal days (PND) 7, 9 and 11. All PCP animals tested in adulthood (PND 53-93) showed deficits in cognitive flexibility, specifically in their ability to shift attentional set, compared to controls. This novel finding is reminiscent of the impairment observed in schizophrenia patients, and supports the validity of the early postnatal PCP regimen as a disease-like model.

AB - Phencyclidine (PCP) was administered to male and female Lister hooded rats on postnatal days (PND) 7, 9 and 11. All PCP animals tested in adulthood (PND 53-93) showed deficits in cognitive flexibility, specifically in their ability to shift attentional set, compared to controls. This novel finding is reminiscent of the impairment observed in schizophrenia patients, and supports the validity of the early postnatal PCP regimen as a disease-like model.

U2 - http://dx.doi.org/10.1016/j.bbr.2008.02.020

DO - http://dx.doi.org/10.1016/j.bbr.2008.02.020

M3 - Journal article

VL - 190

SP - 160

EP - 163

JO - Behavioural Brain Research

JF - Behavioural Brain Research

SN - 0166-4328

IS - 1

ER -

ID: 34046362