Estimates of epilepsy prevalence, psychiatric co-morbidity and cost
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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Estimates of epilepsy prevalence, psychiatric co-morbidity and cost. / Christensen, Jakob; Dreier, Julie Werenberg; Sun, Yuelian; Linehan, Christine; Tomson, Torbjörn; Marson, Anthony; Forsgren, Lars; Granbichler, Claudia A.; Trinka, Eugen; Illiescu, Catrinel; Malmgren, Kristina; Kjellberg, Jakob; Ibsen, Rikke; Jennum, Poul Jorgen; the ESBACE Consortium and ESBACE Collaborators.
I: Seizure, Bind 107, 2023, s. 162-171.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Estimates of epilepsy prevalence, psychiatric co-morbidity and cost
AU - Christensen, Jakob
AU - Dreier, Julie Werenberg
AU - Sun, Yuelian
AU - Linehan, Christine
AU - Tomson, Torbjörn
AU - Marson, Anthony
AU - Forsgren, Lars
AU - Granbichler, Claudia A.
AU - Trinka, Eugen
AU - Illiescu, Catrinel
AU - Malmgren, Kristina
AU - Kjellberg, Jakob
AU - Ibsen, Rikke
AU - Jennum, Poul Jorgen
AU - the ESBACE Consortium and ESBACE Collaborators
N1 - Publisher Copyright: © 2022 The Author(s)
PY - 2023
Y1 - 2023
N2 - Purpose: This study estimated epilepsy prevalence, psychiatric co-morbidity and annual costs associated with epilepsy. Methods: We used Danish national health registers to identify persons diagnosed with epilepsy and psychiatric disorders, and persons using antiseizure medication and persons using drugs for psychiatric disorders. We calculated the prevalence of epilepsy and co-morbid psychiatric disorders in Denmark on December 31, 2016, using information on epilepsy and psychiatric disorders based on combinations of hospital contacts and use of antiseizure and psychoactive medication. Further, direct and indirect annual costs associated with epilepsy were calculated using individual-level data from a range of socioeconomic registers. Results: There were 5,044,367 persons alive and living in Denmark on December 31, 2016, including 33,628 persons with at least one hospital contact with epilepsy in the previous five years (epilepsy prevalence 0.67% (0.69% males; 0.65% females)). Among these persons with epilepsy, we identified 12,562 (37.4%) persons with a psychiatric disorder or use of drugs used for psychiatric disorders as compared with 801,052 (15.9%) persons in the general population. The estimated total annual individual net costs associated with epilepsy was €30,683. Compared with prevalence estimates on December 31, 2006, the prevalence of epilepsy on December 31, 2016, was slightly higher in the older population and slightly lower in children Conclusions: Population estimates from national registers provide epilepsy prevalence estimates of approximately 0.6–0.7% - similar to previous reviews of epilepsy prevalence. In addition, the national sample allowed idenitfication of high prevalence of psychiatric disorders and high societal costs associated with epielspy.
AB - Purpose: This study estimated epilepsy prevalence, psychiatric co-morbidity and annual costs associated with epilepsy. Methods: We used Danish national health registers to identify persons diagnosed with epilepsy and psychiatric disorders, and persons using antiseizure medication and persons using drugs for psychiatric disorders. We calculated the prevalence of epilepsy and co-morbid psychiatric disorders in Denmark on December 31, 2016, using information on epilepsy and psychiatric disorders based on combinations of hospital contacts and use of antiseizure and psychoactive medication. Further, direct and indirect annual costs associated with epilepsy were calculated using individual-level data from a range of socioeconomic registers. Results: There were 5,044,367 persons alive and living in Denmark on December 31, 2016, including 33,628 persons with at least one hospital contact with epilepsy in the previous five years (epilepsy prevalence 0.67% (0.69% males; 0.65% females)). Among these persons with epilepsy, we identified 12,562 (37.4%) persons with a psychiatric disorder or use of drugs used for psychiatric disorders as compared with 801,052 (15.9%) persons in the general population. The estimated total annual individual net costs associated with epilepsy was €30,683. Compared with prevalence estimates on December 31, 2006, the prevalence of epilepsy on December 31, 2016, was slightly higher in the older population and slightly lower in children Conclusions: Population estimates from national registers provide epilepsy prevalence estimates of approximately 0.6–0.7% - similar to previous reviews of epilepsy prevalence. In addition, the national sample allowed idenitfication of high prevalence of psychiatric disorders and high societal costs associated with epielspy.
KW - Cost
KW - Epidemiology
KW - Prevalence
KW - Psychiatric co-morbidity
U2 - 10.1016/j.seizure.2022.06.010
DO - 10.1016/j.seizure.2022.06.010
M3 - Journal article
C2 - 35811222
AN - SCOPUS:85133777678
VL - 107
SP - 162
EP - 171
JO - Seizure : the journal of the British Epilepsy Association
JF - Seizure : the journal of the British Epilepsy Association
SN - 1059-1311
ER -
ID: 331315087