Enhanced uptake and photoactivation of topical methyl aminolevulinate after fractional CO2 laser pretreatment
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Enhanced uptake and photoactivation of topical methyl aminolevulinate after fractional CO2 laser pretreatment. / Haedersdal, M; Katsnelson, J; Sakamoto, F H; Farinelli, W A; Doukas, A G; Tam, J; Anderson, R R.
I: Lasers in Surgery and Medicine, Bind 43, Nr. 8, 2011, s. 804-13.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Enhanced uptake and photoactivation of topical methyl aminolevulinate after fractional CO2 laser pretreatment
AU - Haedersdal, M
AU - Katsnelson, J
AU - Sakamoto, F H
AU - Farinelli, W A
AU - Doukas, A G
AU - Tam, J
AU - Anderson, R R
N1 - Copyright © 2011 Wiley-Liss, Inc.
PY - 2011
Y1 - 2011
N2 - Photodynamic therapy (PDT) of thick skin lesions is limited by topical drug uptake. Ablative fractional resurfacing (AFR) creates vertical channels that may facilitate topical PDT drug penetration and improve PDT-response in deep skin layers. The purpose of this study was to evaluate whether pre-treating the skin with AFR before topically applied methyl aminolevulinate (MAL) could enable a deep PDT-response.
AB - Photodynamic therapy (PDT) of thick skin lesions is limited by topical drug uptake. Ablative fractional resurfacing (AFR) creates vertical channels that may facilitate topical PDT drug penetration and improve PDT-response in deep skin layers. The purpose of this study was to evaluate whether pre-treating the skin with AFR before topically applied methyl aminolevulinate (MAL) could enable a deep PDT-response.
U2 - http://dx.doi.org/10.1002/lsm.21096
DO - http://dx.doi.org/10.1002/lsm.21096
M3 - Journal article
VL - 43
SP - 804
EP - 813
JO - Lasers in Surgery and Medicine
JF - Lasers in Surgery and Medicine
SN - 0196-8092
IS - 8
ER -
ID: 40161115