Effekt af antidepressiv medicin på hjernevolumen
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Effekt af antidepressiv medicin på hjernevolumen. / Videbech, Poul; Yttri, Janne-Elin.
I: Ugeskrift for Laeger, Bind 181, Nr. 38, V02190087, 2019.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Effekt af antidepressiv medicin på hjernevolumen
AU - Videbech, Poul
AU - Yttri, Janne-Elin
PY - 2019
Y1 - 2019
N2 - In this review, we summarise all studies of patients with depression, who have been examined by MRI before and after treatment with antidepressants. None of the studies showed any signs of damage to the brain tissue after treatment. On the contrary, most studies showed increases in hippocampal volume and prefrontal cortices in parallel with response or remission after treatment. As depression in several meta-analyses has been shown to double the risk for dementia, this could have important implications for preventive measures, because, for instance, hippocampal atrophy is seen in both diseases.
AB - In this review, we summarise all studies of patients with depression, who have been examined by MRI before and after treatment with antidepressants. None of the studies showed any signs of damage to the brain tissue after treatment. On the contrary, most studies showed increases in hippocampal volume and prefrontal cortices in parallel with response or remission after treatment. As depression in several meta-analyses has been shown to double the risk for dementia, this could have important implications for preventive measures, because, for instance, hippocampal atrophy is seen in both diseases.
M3 - Tidsskriftartikel
C2 - 31538578
VL - 181
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 38
M1 - V02190087
ER -
ID: 238527547