Effects of physical training on endothelial function and limb blood flow in type 2 diabetes.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Standard
Effects of physical training on endothelial function and limb blood flow in type 2 diabetes. / Sonne, Mette Paulli; Scheede-Bergdahl, Celena; Olsen, David Benee; Højbjerre, Lise; Alibegovic, Amra; Nielsen, Ninna Bo; Stallknecht, Bente; Helge, Jørn Wulff; Vaag, Allan; Dela, Flemming.
I: Applied Physiology, Nutrition and Metabolism, Bind 32, Nr. 5, 2007, s. 936-41.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Effects of physical training on endothelial function and limb blood flow in type 2 diabetes.
AU - Sonne, Mette Paulli
AU - Scheede-Bergdahl, Celena
AU - Olsen, David Benee
AU - Højbjerre, Lise
AU - Alibegovic, Amra
AU - Nielsen, Ninna Bo
AU - Stallknecht, Bente
AU - Helge, Jørn Wulff
AU - Vaag, Allan
AU - Dela, Flemming
N1 - Keywords: Diabetes Mellitus, Type 2; Endothelium, Vascular; Exercise; Humans; Leg; Vasodilation
PY - 2007
Y1 - 2007
N2 - The term "endothelial dysfunction" refers to the inability or attenuated effect of the endothelial cells in participating in the relaxation of the adjacent smooth muscle, thus causing less vasodilation. Although endothelial dysfunction is often seen in patients with type 2 diabetes, it does not necessarily follow that insulin resistance and (or) hyperglycemia is causing the inability to respond properly to vasodilatory stimuli. Rather, this could be related to the impact of concomitant cardiovascular risk factors that are almost invariably present in patients with type 2 diabetes. The impact of physical training - or the opposite, inactivity - on endothelial function is not fully elucidated. Some studies have shown positive effects of physical training, whereas others have not. In general, physical training can improve endothelial function when this is impaired. However, physical training does not seem to have any effect on endothelial function when this is normal.
AB - The term "endothelial dysfunction" refers to the inability or attenuated effect of the endothelial cells in participating in the relaxation of the adjacent smooth muscle, thus causing less vasodilation. Although endothelial dysfunction is often seen in patients with type 2 diabetes, it does not necessarily follow that insulin resistance and (or) hyperglycemia is causing the inability to respond properly to vasodilatory stimuli. Rather, this could be related to the impact of concomitant cardiovascular risk factors that are almost invariably present in patients with type 2 diabetes. The impact of physical training - or the opposite, inactivity - on endothelial function is not fully elucidated. Some studies have shown positive effects of physical training, whereas others have not. In general, physical training can improve endothelial function when this is impaired. However, physical training does not seem to have any effect on endothelial function when this is normal.
U2 - 10.1139/h07-103
DO - 10.1139/h07-103
M3 - Journal article
C2 - 18059619
VL - 32
SP - 936
EP - 941
JO - Applied Physiology, Nutrition and Metabolism
JF - Applied Physiology, Nutrition and Metabolism
SN - 1715-5312
IS - 5
ER -
ID: 8419469