Effect of intermittent versus continuous parathyroid hormone in the cardiovascular system of rats
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Effect of intermittent versus continuous parathyroid hormone in the cardiovascular system of rats. / Smajilovic, Sanela; Schaal-Jensen, Rasmus; Jabbari, Reza; Smajilovic, Una; Haunso, Stig; Tfelt-Hansen, Jacob; Schaal-Jensen, Rasmus.
I: Open Cardiovascular Medicine Journal, Bind 4, 01.01.2010, s. 110-6.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Effect of intermittent versus continuous parathyroid hormone in the cardiovascular system of rats
AU - Smajilovic, Sanela
AU - Schaal-Jensen, Rasmus
AU - Jabbari, Reza
AU - Smajilovic, Una
AU - Haunso, Stig
AU - Tfelt-Hansen, Jacob
AU - Schaal-Jensen, Rasmus
PY - 2010/1/1
Y1 - 2010/1/1
N2 - PTH increases ionic calcium concentration in the serum, acting primarily on bone and kidney cells through the type 1 PTH receptor. Interestingly, PTH stimulates bone formation when administrated intermittently but causes severe bone loss with continuous administration. Daily injections of PTH are used as the most promising anabolic agent in the treatment of severe osteoporosis. Elevated PTH is reported an independent risk factor for left ventricle hypertrophy.
AB - PTH increases ionic calcium concentration in the serum, acting primarily on bone and kidney cells through the type 1 PTH receptor. Interestingly, PTH stimulates bone formation when administrated intermittently but causes severe bone loss with continuous administration. Daily injections of PTH are used as the most promising anabolic agent in the treatment of severe osteoporosis. Elevated PTH is reported an independent risk factor for left ventricle hypertrophy.
U2 - http://dx.doi.org/10.2174/1874192401004010110
DO - http://dx.doi.org/10.2174/1874192401004010110
M3 - Journal article
VL - 4
SP - 110
EP - 116
JO - The Open Cardiovascular Medicine Journal
JF - The Open Cardiovascular Medicine Journal
SN - 1874-1924
ER -
ID: 34190493