Effect of complementary food with small amounts of freshwater fish on whole blood n-3 fatty acids in Cambodian infants age 6–15 months
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Effect of complementary food with small amounts of freshwater fish on whole blood n-3 fatty acids in Cambodian infants age 6–15 months. / Nurhasan, Mulia; Roos, Nanna; Skau, Jutta Kloppenborg Heick; Wieringa, Frank T; Friis, Henrik; Michaelsen, Kim F.; Dijkhuizen, Marjoleine Amma; Stark, Ken D; Ritz, Christian; Chhoun, Chamnan; Lauritzen, Lotte.
I: Prostaglandins, Leukotrienes & Essential Fatty Acids, Bind 135, 2018, s. 92-101.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Effect of complementary food with small amounts of freshwater fish on whole blood n-3 fatty acids in Cambodian infants age 6–15 months
AU - Nurhasan, Mulia
AU - Roos, Nanna
AU - Skau, Jutta Kloppenborg Heick
AU - Wieringa, Frank T
AU - Friis, Henrik
AU - Michaelsen, Kim F.
AU - Dijkhuizen, Marjoleine Amma
AU - Stark, Ken D
AU - Ritz, Christian
AU - Chhoun, Chamnan
AU - Lauritzen, Lotte
N1 - CURIS 2018 NEXS 255
PY - 2018
Y1 - 2018
N2 - The impact of freshwater fish consumption on the status of long-chain n-3 fatty acids (n-3 LCPUFA) in infants in landlocked, low-income populations is unknown. We used secondary data from a randomized, single-blinded, controlled trial to evaluate the impact of daily consumption of complementary food products with small amounts of freshwater fish on whole blood n-3 LCPUFA in Cambodian infants. Infants (n = 419), received daily, one of four food products for 9 months. Two products contained freshwater fish: WinFood (10% fish by dry weight) and WinFood-L (12% fish by dry weight), while two products were non-fish-based: corn-soy blends (CSB+ and CSB++). Whole blood fatty acids and breastfeeding status were assessed at baseline and endline of the intervention. The WinFood products contributed to an estimated maximum intake of 86.5 mg/day n-3 LCPUFA. There was no difference in whole blood n-3 LCPUFA among the four intervention groups or between the fish-based and the non-fish-based groups (p ≥ 0.142). At endline, 71% of the children were still breastfed. Interaction analyses indicated a lower ratio of n-6/n-3 PUFA in non-breastfed infants in the WinFood groups compared to the CSB groups (pinteraction= 0.026). Thus, a high intake of n-3 LCPUFA from breastmilk may have blurred a potential impact of small amounts of freshwater fish effect on n-3 LCPUFA status in Cambodian infants.
AB - The impact of freshwater fish consumption on the status of long-chain n-3 fatty acids (n-3 LCPUFA) in infants in landlocked, low-income populations is unknown. We used secondary data from a randomized, single-blinded, controlled trial to evaluate the impact of daily consumption of complementary food products with small amounts of freshwater fish on whole blood n-3 LCPUFA in Cambodian infants. Infants (n = 419), received daily, one of four food products for 9 months. Two products contained freshwater fish: WinFood (10% fish by dry weight) and WinFood-L (12% fish by dry weight), while two products were non-fish-based: corn-soy blends (CSB+ and CSB++). Whole blood fatty acids and breastfeeding status were assessed at baseline and endline of the intervention. The WinFood products contributed to an estimated maximum intake of 86.5 mg/day n-3 LCPUFA. There was no difference in whole blood n-3 LCPUFA among the four intervention groups or between the fish-based and the non-fish-based groups (p ≥ 0.142). At endline, 71% of the children were still breastfed. Interaction analyses indicated a lower ratio of n-6/n-3 PUFA in non-breastfed infants in the WinFood groups compared to the CSB groups (pinteraction= 0.026). Thus, a high intake of n-3 LCPUFA from breastmilk may have blurred a potential impact of small amounts of freshwater fish effect on n-3 LCPUFA status in Cambodian infants.
KW - Breastfeeding
KW - Docosahexaenoic acid
KW - Fish-based complementary food
KW - n-3 LCPUFA status
U2 - 10.1016/j.plefa.2018.07.002
DO - 10.1016/j.plefa.2018.07.002
M3 - Journal article
C2 - 30103938
AN - SCOPUS:85050276902
VL - 135
SP - 92
EP - 101
JO - Prostaglandins, Leukotrienes & Essential Fatty Acids
JF - Prostaglandins, Leukotrienes & Essential Fatty Acids
SN - 0952-3278
ER -
ID: 200537707