EAACI Molecular Allergology User's Guide 2.0
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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EAACI Molecular Allergology User's Guide 2.0. / Dramburg, Stephanie; Hilger, Christiane; Santos, Alexandra F.; de las Vecillas, Leticia; Aalberse, Rob C.; Acevedo, Nathalie; Aglas, Lorenz; Altmann, Friedrich; Arruda, Karla L.; Asero, Riccardo; Ballmer-Weber, Barbara; Barber, Domingo; Beyer, Kirsten; Biedermann, Tilo; Bilo, Maria Beatrice; Blank, Simon; Bosshard, Philipp P; Breiteneder, Heimo; Brough, Helen A.; Bublin, Merima; Campbell, Dianne; Caraballo, Luis; Caubet, Jean Christoph; Celi, Giorgio; Chapman, Martin D.; Chruszcz, Maksymilian; Custovic, Adnan; Czolk, Rebecca; Davies, Janet; Douladiris, Nikolaos; Eberlein, Bernadette; Ebisawa, Motohiro; Ehlers, Anna; Eigenmann, Philippe; Gadermaier, Gabriele; Giovannini, Mattia; Gomez, Francisca; Grohman, Rebecca; Guillet, Carole; Hafner, Christine; Hamilton, Robert G; Hauser, Michael; Hawranek, Thomas; Hoffmann, Hans Jürgen; Holzhauser, Thomas; Iizuka, Tomona; Jacquet, Alain; Jakob, Thilo; Janssen-Weets, Bente; Jappe, Uta; Jutel, Marek; Kalic, Tanja; Kamath, Sandip; Kespohl, Sabine; Kleine-Tebbe, Jörg; Knol, Edward; Knulst, André; Konradsen, Jon R.; Korošec, Peter; Kuehn, Annette; Lack, Gideon; Le, Thuy My; Lopata, Andreas; Luengo, Olga; Mäkelä, Mika; Marra, Alessandro Maria; Mills, Clare; Morisset, Martine; Muraro, Antonella; Nowak-Wegrzyn, Anna; Nugraha, Roni; Ollert, Markus; Palosuo, Kati; Pastorello, Elide Anna; Patil, Sarita Ulhas; Platts-Mills, Thomas; Pomés, Anna; Poncet, Pascal; Potapova, Ekaterina; Poulsen, Lars K.; Radauer, Christian; Radulovic, Suzana; Raulf, Monika; Rougé, Pierre; Sastre, Joaquin; Sato, Sakura; Scala, Enrico; Schmid, Johannes M.; Schmid-Grendelmeier, Peter; Schrama, Denise; Sénéchal, Hélène; Traidl-Hoffmann, Claudia; Valverde-Monge, Marcela; van Hage, Marianne; van Ree, Ronald; Verhoeckx, Kitty; Vieths, Stefan; Wickman, Magnus; Zakzuk, Josefina; Matricardi, Paolo M; Hoffmann-Sommergruber, Karin.
I: Pediatric Allergy and Immunology, Bind 34, Nr. S28, e13854, 2023.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - EAACI Molecular Allergology User's Guide 2.0
AU - Dramburg, Stephanie
AU - Hilger, Christiane
AU - Santos, Alexandra F.
AU - de las Vecillas, Leticia
AU - Aalberse, Rob C.
AU - Acevedo, Nathalie
AU - Aglas, Lorenz
AU - Altmann, Friedrich
AU - Arruda, Karla L.
AU - Asero, Riccardo
AU - Ballmer-Weber, Barbara
AU - Barber, Domingo
AU - Beyer, Kirsten
AU - Biedermann, Tilo
AU - Bilo, Maria Beatrice
AU - Blank, Simon
AU - Bosshard, Philipp P
AU - Breiteneder, Heimo
AU - Brough, Helen A.
AU - Bublin, Merima
AU - Campbell, Dianne
AU - Caraballo, Luis
AU - Caubet, Jean Christoph
AU - Celi, Giorgio
AU - Chapman, Martin D.
AU - Chruszcz, Maksymilian
AU - Custovic, Adnan
AU - Czolk, Rebecca
AU - Davies, Janet
AU - Douladiris, Nikolaos
AU - Eberlein, Bernadette
AU - Ebisawa, Motohiro
AU - Ehlers, Anna
AU - Eigenmann, Philippe
AU - Gadermaier, Gabriele
AU - Giovannini, Mattia
AU - Gomez, Francisca
AU - Grohman, Rebecca
AU - Guillet, Carole
AU - Hafner, Christine
AU - Hamilton, Robert G
AU - Hauser, Michael
AU - Hawranek, Thomas
AU - Hoffmann, Hans Jürgen
AU - Holzhauser, Thomas
AU - Iizuka, Tomona
AU - Jacquet, Alain
AU - Jakob, Thilo
AU - Janssen-Weets, Bente
AU - Jappe, Uta
AU - Jutel, Marek
AU - Kalic, Tanja
AU - Kamath, Sandip
AU - Kespohl, Sabine
AU - Kleine-Tebbe, Jörg
AU - Knol, Edward
AU - Knulst, André
AU - Konradsen, Jon R.
AU - Korošec, Peter
AU - Kuehn, Annette
AU - Lack, Gideon
AU - Le, Thuy My
AU - Lopata, Andreas
AU - Luengo, Olga
AU - Mäkelä, Mika
AU - Marra, Alessandro Maria
AU - Mills, Clare
AU - Morisset, Martine
AU - Muraro, Antonella
AU - Nowak-Wegrzyn, Anna
AU - Nugraha, Roni
AU - Ollert, Markus
AU - Palosuo, Kati
AU - Pastorello, Elide Anna
AU - Patil, Sarita Ulhas
AU - Platts-Mills, Thomas
AU - Pomés, Anna
AU - Poncet, Pascal
AU - Potapova, Ekaterina
AU - Poulsen, Lars K.
AU - Radauer, Christian
AU - Radulovic, Suzana
AU - Raulf, Monika
AU - Rougé, Pierre
AU - Sastre, Joaquin
AU - Sato, Sakura
AU - Scala, Enrico
AU - Schmid, Johannes M.
AU - Schmid-Grendelmeier, Peter
AU - Schrama, Denise
AU - Sénéchal, Hélène
AU - Traidl-Hoffmann, Claudia
AU - Valverde-Monge, Marcela
AU - van Hage, Marianne
AU - van Ree, Ronald
AU - Verhoeckx, Kitty
AU - Vieths, Stefan
AU - Wickman, Magnus
AU - Zakzuk, Josefina
AU - Matricardi, Paolo M
AU - Hoffmann-Sommergruber, Karin
N1 - Publisher Copyright: © 2023 The Authors. Pediatric Allergy and Immunology published by European Academy of Allergy and Clinical Immunology and John Wiley & Sons Ltd.
PY - 2023
Y1 - 2023
N2 - Since the discovery of immunoglobulin E (IgE) as a mediator of allergic diseases in 1967, our knowledge about the immunological mechanisms of IgE-mediated allergies has remarkably increased. In addition to understanding the immune response and clinical symptoms, allergy diagnosis and management depend strongly on the precise identification of the elicitors of the IgE-mediated allergic reaction. In the past four decades, innovations in bioscience and technology have facilitated the identification and production of well-defined, highly pure molecules for component-resolved diagnosis (CRD), allowing a personalized diagnosis and management of the allergic disease for individual patients. The first edition of the “EAACI Molecular Allergology User's Guide” (MAUG) in 2016 rapidly became a key reference for clinicians, scientists, and interested readers with a background in allergology, immunology, biology, and medicine. Nevertheless, the field of molecular allergology is moving fast, and after 6 years, a new EAACI Taskforce was established to provide an updated document. The Molecular Allergology User's Guide 2.0 summarizes state-of-the-art information on allergen molecules, their clinical relevance, and their application in diagnostic algorithms for clinical practice. It is designed for both, clinicians and scientists, guiding health care professionals through the overwhelming list of different allergen molecules available for testing. Further, it provides diagnostic algorithms on the clinical relevance of allergenic molecules and gives an overview of their biology, the basic mechanisms of test formats, and the application of tests to measure allergen exposure.
AB - Since the discovery of immunoglobulin E (IgE) as a mediator of allergic diseases in 1967, our knowledge about the immunological mechanisms of IgE-mediated allergies has remarkably increased. In addition to understanding the immune response and clinical symptoms, allergy diagnosis and management depend strongly on the precise identification of the elicitors of the IgE-mediated allergic reaction. In the past four decades, innovations in bioscience and technology have facilitated the identification and production of well-defined, highly pure molecules for component-resolved diagnosis (CRD), allowing a personalized diagnosis and management of the allergic disease for individual patients. The first edition of the “EAACI Molecular Allergology User's Guide” (MAUG) in 2016 rapidly became a key reference for clinicians, scientists, and interested readers with a background in allergology, immunology, biology, and medicine. Nevertheless, the field of molecular allergology is moving fast, and after 6 years, a new EAACI Taskforce was established to provide an updated document. The Molecular Allergology User's Guide 2.0 summarizes state-of-the-art information on allergen molecules, their clinical relevance, and their application in diagnostic algorithms for clinical practice. It is designed for both, clinicians and scientists, guiding health care professionals through the overwhelming list of different allergen molecules available for testing. Further, it provides diagnostic algorithms on the clinical relevance of allergenic molecules and gives an overview of their biology, the basic mechanisms of test formats, and the application of tests to measure allergen exposure.
KW - allergy
KW - allergy diagnosis
KW - anaphylaxis
KW - asthma
KW - atopic dermatitis
KW - basophil activation test
KW - component-resolved diagnosis
KW - cross-reactive carbohydrates
KW - diagnostic algorithms
KW - food allergy
KW - gibberellin-regulated proteins
KW - IgE
KW - IgE cross-reactivity
KW - lipocalins
KW - microarray
KW - molecular allergology
KW - non-specific lipid transfer proteins
KW - oleosins
KW - pan-allergens
KW - parvalbumins
KW - pathogenesis-related protein family 10
KW - polcalcins
KW - pollen allergy
KW - precision medicine
KW - profilins
KW - seed storage proteins
KW - serum albumins
KW - tropomyosins
U2 - 10.1111/pai.13854
DO - 10.1111/pai.13854
M3 - Journal article
C2 - 37186333
AN - SCOPUS:85153787295
VL - 34
JO - Pediatric Allergy and Immunology, Supplement
JF - Pediatric Allergy and Immunology, Supplement
SN - 0906-5784
IS - S28
M1 - e13854
ER -
ID: 347302890