Dynamic switching between semantic and episodic memory systems
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Standard
Dynamic switching between semantic and episodic memory systems. / Kompus, Kristiina; Olsson, Carl Johan; Larsson, Anne; Nyberg, Lars.
I: Neuropsychologia, Bind 47, Nr. 11, 2009, s. 2252-2260.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Dynamic switching between semantic and episodic memory systems
AU - Kompus, Kristiina
AU - Olsson, Carl Johan
AU - Larsson, Anne
AU - Nyberg, Lars
N1 - Funding Information: This work was funded by a grant from the Joint Committee for Nordic Research Councils in the Humanities and the Social Sciences to Lars Nyberg for a Nordic Center of Excellence (NCoE) in Cognitive Control.
PY - 2009
Y1 - 2009
N2 - It has been suggested that episodic and semantic long-term memory systems interact during retrieval. Here we examined the flexibility of memory retrieval in an associative task taxing memories of different strength, assumed to differentially engage episodic and semantic memory. Healthy volunteers were pre-trained on a set of 36 face-name pairs over a 6-week period. Another set of 36 items was shown only once during the same time period. About 3 months after the training period all items were presented in a randomly intermixed order in an event-related fMRI study of face-name memory. Once presented items differentially activated anterior cingulate cortex and a right prefrontal region that previously have been associated with episodic retrieval mode. High-familiar items were associated with stronger activation of posterior cortices and a left frontal region. These findings fit a model of memory retrieval by which early processes determine, on a trial-by-trial basis, if the task can be solved by the default semantic system. If not, there is a dynamic shift to cognitive control processes that guide retrieval from episodic memory.
AB - It has been suggested that episodic and semantic long-term memory systems interact during retrieval. Here we examined the flexibility of memory retrieval in an associative task taxing memories of different strength, assumed to differentially engage episodic and semantic memory. Healthy volunteers were pre-trained on a set of 36 face-name pairs over a 6-week period. Another set of 36 items was shown only once during the same time period. About 3 months after the training period all items were presented in a randomly intermixed order in an event-related fMRI study of face-name memory. Once presented items differentially activated anterior cingulate cortex and a right prefrontal region that previously have been associated with episodic retrieval mode. High-familiar items were associated with stronger activation of posterior cortices and a left frontal region. These findings fit a model of memory retrieval by which early processes determine, on a trial-by-trial basis, if the task can be solved by the default semantic system. If not, there is a dynamic shift to cognitive control processes that guide retrieval from episodic memory.
KW - Episodic
KW - fMRI
KW - Learning
KW - Memory
KW - Prefrontal
U2 - 10.1016/j.neuropsychologia.2008.11.031
DO - 10.1016/j.neuropsychologia.2008.11.031
M3 - Journal article
C2 - 19109984
AN - SCOPUS:67349232794
VL - 47
SP - 2252
EP - 2260
JO - Neuropsychologia
JF - Neuropsychologia
SN - 0028-3932
IS - 11
ER -
ID: 339262068