Dynamic Optical Coherence Tomography in Dermatology
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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Dynamic Optical Coherence Tomography in Dermatology. / Ulrich, Martina; Themstrup, Lotte; De Carvalho, Nathalie; Manfredi, Marco; Grana, Costantino; Ciardo, Silvana; Kästle, Raphaela; Holmes, Jon; Whitehead, Richard; Jemec, Gregor B.E.; Pellacani, Giovanni; Welzel, Julia.
I: Dermatology, Bind 232, Nr. 3, 01.06.2016, s. 298-311.Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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TY - JOUR
T1 - Dynamic Optical Coherence Tomography in Dermatology
AU - Ulrich, Martina
AU - Themstrup, Lotte
AU - De Carvalho, Nathalie
AU - Manfredi, Marco
AU - Grana, Costantino
AU - Ciardo, Silvana
AU - Kästle, Raphaela
AU - Holmes, Jon
AU - Whitehead, Richard
AU - Jemec, Gregor B.E.
AU - Pellacani, Giovanni
AU - Welzel, Julia
PY - 2016/6/1
Y1 - 2016/6/1
N2 - Optical coherence tomography (OCT) represents a non-invasive imaging technology, which may be applied to the diagnosis of non-melanoma skin cancer and which has recently been shown to improve the diagnostic accuracy of basal cell carcinoma. Technical developments of OCT continue to expand the applicability of OCT for different neoplastic and inflammatory skin diseases. Of these, dynamic OCT (D-OCT) based on speckle variance OCT is of special interest as it allows the in vivo evaluation of blood vessels and their distribution within specific lesions, providing additional functional information and consequently greater density of data. In an effort to assess the potential of D-OCT for future scientific and clinical studies, we have therefore reviewed the literature and preliminary unpublished data on the visualization of the microvasculature using D-OCT. Information on D-OCT in skin cancers including melanoma, as well as in a variety of other skin diseases, is presented in an atlas. Possible diagnostic features are suggested, although these require additional validation.
AB - Optical coherence tomography (OCT) represents a non-invasive imaging technology, which may be applied to the diagnosis of non-melanoma skin cancer and which has recently been shown to improve the diagnostic accuracy of basal cell carcinoma. Technical developments of OCT continue to expand the applicability of OCT for different neoplastic and inflammatory skin diseases. Of these, dynamic OCT (D-OCT) based on speckle variance OCT is of special interest as it allows the in vivo evaluation of blood vessels and their distribution within specific lesions, providing additional functional information and consequently greater density of data. In an effort to assess the potential of D-OCT for future scientific and clinical studies, we have therefore reviewed the literature and preliminary unpublished data on the visualization of the microvasculature using D-OCT. Information on D-OCT in skin cancers including melanoma, as well as in a variety of other skin diseases, is presented in an atlas. Possible diagnostic features are suggested, although these require additional validation.
KW - Actinic keratosis
KW - Basal cell carcinoma
KW - Diagnosis
KW - Melanoma
KW - Optical coherence tomography
KW - Prognosis
KW - Skin cancer
KW - Squamous cell carcinoma
KW - Vascularity
U2 - 10.1159/000444706
DO - 10.1159/000444706
M3 - Review
C2 - 27104356
AN - SCOPUS:84975059916
VL - 232
SP - 298
EP - 311
JO - Dermatology
JF - Dermatology
SN - 1018-8665
IS - 3
ER -
ID: 179050097