Does hydroxyapatite coating of uncemented cups improve long-term survival? An analysis of 28,605 primary total hip arthroplasty procedures from the Nordic Arthroplasty Register Association (NARA)

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Standard

Does hydroxyapatite coating of uncemented cups improve long-term survival? An analysis of 28,605 primary total hip arthroplasty procedures from the Nordic Arthroplasty Register Association (NARA). / Lazarinis, Stergios; Mäkelä, Keijo T; Eskelinen, Antti; Havelin, Leif; Hallan, Geir; Overgaard, Søren; Pedersen, Alma Becic; Kärrholm, Johan; Hailer, Nils P.

I: Osteoarthritis and Cartilage, Bind 25, Nr. 12, 12.2017, s. 1980-1987.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Lazarinis, S, Mäkelä, KT, Eskelinen, A, Havelin, L, Hallan, G, Overgaard, S, Pedersen, AB, Kärrholm, J & Hailer, NP 2017, 'Does hydroxyapatite coating of uncemented cups improve long-term survival? An analysis of 28,605 primary total hip arthroplasty procedures from the Nordic Arthroplasty Register Association (NARA)', Osteoarthritis and Cartilage, bind 25, nr. 12, s. 1980-1987. https://doi.org/10.1016/j.joca.2017.08.001

APA

Lazarinis, S., Mäkelä, K. T., Eskelinen, A., Havelin, L., Hallan, G., Overgaard, S., Pedersen, A. B., Kärrholm, J., & Hailer, N. P. (2017). Does hydroxyapatite coating of uncemented cups improve long-term survival? An analysis of 28,605 primary total hip arthroplasty procedures from the Nordic Arthroplasty Register Association (NARA). Osteoarthritis and Cartilage, 25(12), 1980-1987. https://doi.org/10.1016/j.joca.2017.08.001

Vancouver

Lazarinis S, Mäkelä KT, Eskelinen A, Havelin L, Hallan G, Overgaard S o.a. Does hydroxyapatite coating of uncemented cups improve long-term survival? An analysis of 28,605 primary total hip arthroplasty procedures from the Nordic Arthroplasty Register Association (NARA). Osteoarthritis and Cartilage. 2017 dec.;25(12):1980-1987. https://doi.org/10.1016/j.joca.2017.08.001

Author

Lazarinis, Stergios ; Mäkelä, Keijo T ; Eskelinen, Antti ; Havelin, Leif ; Hallan, Geir ; Overgaard, Søren ; Pedersen, Alma Becic ; Kärrholm, Johan ; Hailer, Nils P. / Does hydroxyapatite coating of uncemented cups improve long-term survival? An analysis of 28,605 primary total hip arthroplasty procedures from the Nordic Arthroplasty Register Association (NARA). I: Osteoarthritis and Cartilage. 2017 ; Bind 25, Nr. 12. s. 1980-1987.

Bibtex

@article{528db186f1194341b47d2ba85d3127af,
title = "Does hydroxyapatite coating of uncemented cups improve long-term survival?: An analysis of 28,605 primary total hip arthroplasty procedures from the Nordic Arthroplasty Register Association (NARA)",
abstract = "Objective It is unclear whether hydroxyapatite (HA) coating of uncemented cups used in primary total hip arthroplasty (THA) improves bone ingrowth and reduces the risk of aseptic loosening. We therefore investigated survival of different uncemented cups that were available with or without HA coating. Method We investigated three different cup types used with or without HA coating registered in the Nordic Arthroplasty Register Association (NARA) database that were inserted due to osteoarthritis (n = 28,605). Cumulative survival rates and adjusted hazard ratios (HRs) for the risk of revision were calculated. Results Unadjusted 13-year survival for cup revision due to aseptic loosening was 97.9% (CI: 96.5–99.4) for uncoated and 97.8% (CI: 96.3–99.4) for HA-coated cups. Adjusted HRs were 0.66 (CI 0.42–1.04) for the presence of HA coating during the first 10 years and 0.87 (CI 0.14–5.38) from year 10–13, compared with uncoated cups. When considering the endpoint cup revision for any reason, unadjusted 13-year survival was similar for uncoated (92.5% [CI: 90.1–94.9]) and HA-coated (94.7% [CI: 93.2–96.3]) cups. The risk of revision of any component due to infection was higher in THA with HA-coated cups than in THA with uncoated cups (adjusted HR 1.4 [CI 1.1–1.9]). Conclusions HA-coated cups have a similar risk of aseptic loosening as uncoated cups, thus the use of HA coating seems to not confer any added value in terms of implant stability. The risk of infection seemed higher in THA with use of HA-coated cups, an observation that must be investigated further.",
author = "Stergios Lazarinis and M{\"a}kel{\"a}, {Keijo T} and Antti Eskelinen and Leif Havelin and Geir Hallan and S{\o}ren Overgaard and Pedersen, {Alma Becic} and Johan K{\"a}rrholm and Hailer, {Nils P}",
note = "Copyright {\textcopyright} 2017. Published by Elsevier Ltd.",
year = "2017",
month = dec,
doi = "10.1016/j.joca.2017.08.001",
language = "English",
volume = "25",
pages = "1980--1987",
journal = "Osteoarthritis and Cartilage",
issn = "1063-4584",
publisher = "Elsevier",
number = "12",

}

RIS

TY - JOUR

T1 - Does hydroxyapatite coating of uncemented cups improve long-term survival?

T2 - An analysis of 28,605 primary total hip arthroplasty procedures from the Nordic Arthroplasty Register Association (NARA)

AU - Lazarinis, Stergios

AU - Mäkelä, Keijo T

AU - Eskelinen, Antti

AU - Havelin, Leif

AU - Hallan, Geir

AU - Overgaard, Søren

AU - Pedersen, Alma Becic

AU - Kärrholm, Johan

AU - Hailer, Nils P

N1 - Copyright © 2017. Published by Elsevier Ltd.

PY - 2017/12

Y1 - 2017/12

N2 - Objective It is unclear whether hydroxyapatite (HA) coating of uncemented cups used in primary total hip arthroplasty (THA) improves bone ingrowth and reduces the risk of aseptic loosening. We therefore investigated survival of different uncemented cups that were available with or without HA coating. Method We investigated three different cup types used with or without HA coating registered in the Nordic Arthroplasty Register Association (NARA) database that were inserted due to osteoarthritis (n = 28,605). Cumulative survival rates and adjusted hazard ratios (HRs) for the risk of revision were calculated. Results Unadjusted 13-year survival for cup revision due to aseptic loosening was 97.9% (CI: 96.5–99.4) for uncoated and 97.8% (CI: 96.3–99.4) for HA-coated cups. Adjusted HRs were 0.66 (CI 0.42–1.04) for the presence of HA coating during the first 10 years and 0.87 (CI 0.14–5.38) from year 10–13, compared with uncoated cups. When considering the endpoint cup revision for any reason, unadjusted 13-year survival was similar for uncoated (92.5% [CI: 90.1–94.9]) and HA-coated (94.7% [CI: 93.2–96.3]) cups. The risk of revision of any component due to infection was higher in THA with HA-coated cups than in THA with uncoated cups (adjusted HR 1.4 [CI 1.1–1.9]). Conclusions HA-coated cups have a similar risk of aseptic loosening as uncoated cups, thus the use of HA coating seems to not confer any added value in terms of implant stability. The risk of infection seemed higher in THA with use of HA-coated cups, an observation that must be investigated further.

AB - Objective It is unclear whether hydroxyapatite (HA) coating of uncemented cups used in primary total hip arthroplasty (THA) improves bone ingrowth and reduces the risk of aseptic loosening. We therefore investigated survival of different uncemented cups that were available with or without HA coating. Method We investigated three different cup types used with or without HA coating registered in the Nordic Arthroplasty Register Association (NARA) database that were inserted due to osteoarthritis (n = 28,605). Cumulative survival rates and adjusted hazard ratios (HRs) for the risk of revision were calculated. Results Unadjusted 13-year survival for cup revision due to aseptic loosening was 97.9% (CI: 96.5–99.4) for uncoated and 97.8% (CI: 96.3–99.4) for HA-coated cups. Adjusted HRs were 0.66 (CI 0.42–1.04) for the presence of HA coating during the first 10 years and 0.87 (CI 0.14–5.38) from year 10–13, compared with uncoated cups. When considering the endpoint cup revision for any reason, unadjusted 13-year survival was similar for uncoated (92.5% [CI: 90.1–94.9]) and HA-coated (94.7% [CI: 93.2–96.3]) cups. The risk of revision of any component due to infection was higher in THA with HA-coated cups than in THA with uncoated cups (adjusted HR 1.4 [CI 1.1–1.9]). Conclusions HA-coated cups have a similar risk of aseptic loosening as uncoated cups, thus the use of HA coating seems to not confer any added value in terms of implant stability. The risk of infection seemed higher in THA with use of HA-coated cups, an observation that must be investigated further.

U2 - 10.1016/j.joca.2017.08.001

DO - 10.1016/j.joca.2017.08.001

M3 - Journal article

C2 - 28802851

VL - 25

SP - 1980

EP - 1987

JO - Osteoarthritis and Cartilage

JF - Osteoarthritis and Cartilage

SN - 1063-4584

IS - 12

ER -

ID: 252058885