TY - JOUR

T1 - Diagnosis and management of migraine in ten steps

AU - Eigenbrodt, Anna K.

AU - Ashina, Håkan

AU - Khan, Sabrina

AU - Diener, Hans Christoph

AU - Mitsikostas, Dimos D.

AU - Sinclair, Alexandra J.

AU - Pozo-Rosich, Patricia

AU - Martelletti, Paolo

AU - Ducros, Anne

AU - Lantéri-Minet, Michel

AU - Braschinsky, Mark

AU - del Rio, Margarita Sanchez

AU - Daniel, Oved

AU - Özge, Aynur

AU - Mammadbayli, Ayten

AU - Arons, Mihails

AU - Skorobogatykh, Kirill

AU - Romanenko, Vladimir

AU - Terwindt, Gisela M.

AU - Paemeleire, Koen

AU - Sacco, Simona

AU - Reuter, Uwe

AU - Lampl, Christian

AU - Schytz, Henrik W.

AU - Katsarava, Zaza

AU - Steiner, Timothy J.

AU - Ashina, Messoud

N1 - Publisher Copyright: © 2021, The Author(s).

PY - 2021/8

Y1 - 2021/8

N2 - Migraine is a disabling primary headache disorder that directly affects more than one billion people worldwide. Despite its widespread prevalence, migraine remains under-diagnosed and under-treated. To support clinical decision-making, we convened a European panel of experts to develop a ten-step approach to the diagnosis and management of migraine. Each step was established by expert consensus and supported by a review of current literature, and the Consensus Statement is endorsed by the European Headache Federation and the European Academy of Neurology. In this Consensus Statement, we introduce typical clinical features, diagnostic criteria and differential diagnoses of migraine. We then emphasize the value of patient centricity and patient education to ensure treatment adherence and satisfaction with care provision. Further, we outline best practices for acute and preventive treatment of migraine in various patient populations, including adults, children and adolescents, pregnant and breastfeeding women, and older people. In addition, we provide recommendations for evaluating treatment response and managing treatment failure. Lastly, we discuss the management of complications and comorbidities as well as the importance of planning long-term follow-up.

AB - Migraine is a disabling primary headache disorder that directly affects more than one billion people worldwide. Despite its widespread prevalence, migraine remains under-diagnosed and under-treated. To support clinical decision-making, we convened a European panel of experts to develop a ten-step approach to the diagnosis and management of migraine. Each step was established by expert consensus and supported by a review of current literature, and the Consensus Statement is endorsed by the European Headache Federation and the European Academy of Neurology. In this Consensus Statement, we introduce typical clinical features, diagnostic criteria and differential diagnoses of migraine. We then emphasize the value of patient centricity and patient education to ensure treatment adherence and satisfaction with care provision. Further, we outline best practices for acute and preventive treatment of migraine in various patient populations, including adults, children and adolescents, pregnant and breastfeeding women, and older people. In addition, we provide recommendations for evaluating treatment response and managing treatment failure. Lastly, we discuss the management of complications and comorbidities as well as the importance of planning long-term follow-up.

U2 - 10.1038/s41582-021-00509-5

DO - 10.1038/s41582-021-00509-5

M3 - Review

C2 - 34145431

AN - SCOPUS:85108248638

VL - 17

SP - 501

EP - 514

JO - Nature Reviews. Neurology

JF - Nature Reviews. Neurology

SN - 1759-4758

IS - 8

ER -