Dendrimers in drug delivery
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Dendrimers in drug delivery. / Mejlsøe, Søren Leth; Christensen, Jørn B.
Advanced and Modern approaches for Drug Delivery. Elsevier, 2023. s. 357-387.Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › fagfællebedømt
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TY - CHAP
T1 - Dendrimers in drug delivery
AU - Mejlsøe, Søren Leth
AU - Christensen, Jørn B.
N1 - Publisher Copyright: © 2023 Elsevier Inc. All rights reserved.
PY - 2023
Y1 - 2023
N2 - A dendrimer is a molecular architecture leading to macromolecules that in size and shape are similar to globular proteins having a spherical structure with a large number of surface groups as well as internal cavities. Size is an important factor for biological properties such as half-life in the blood stream, modes of excretion, and cellular trafficking and given that dendrimers cover a size range of 1-10nm as well as being able to form self-assembled structures, gives a wide pallet for using dendrimers for drug delivery in medicine.
AB - A dendrimer is a molecular architecture leading to macromolecules that in size and shape are similar to globular proteins having a spherical structure with a large number of surface groups as well as internal cavities. Size is an important factor for biological properties such as half-life in the blood stream, modes of excretion, and cellular trafficking and given that dendrimers cover a size range of 1-10nm as well as being able to form self-assembled structures, gives a wide pallet for using dendrimers for drug delivery in medicine.
KW - Antimicrobial agents
KW - Chemotherapy
KW - Dendrimers
KW - Dental applications
KW - Drug delivery
U2 - 10.1016/B978-0-323-91668-4.00005-8
DO - 10.1016/B978-0-323-91668-4.00005-8
M3 - Book chapter
AN - SCOPUS:85176872855
SN - 9780323972192
SP - 357
EP - 387
BT - Advanced and Modern approaches for Drug Delivery
PB - Elsevier
ER -
ID: 374454514