Cryptopharmaceuticals: increasing the safety of medication by a blockchain of pharmaceutical products
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Cryptopharmaceuticals: increasing the safety of medication by a blockchain of pharmaceutical products. / Nørfeldt, Lasse; Bøtker, Johan; Edinger, Magnus; Genina, Natalja; Rantanen, Jukka.
I: Journal of Pharmaceutical Sciences, Bind 108, Nr. 9, 2019, s. 2838–2841.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Cryptopharmaceuticals: increasing the safety of medication by a blockchain of pharmaceutical products
AU - Nørfeldt, Lasse
AU - Bøtker, Johan
AU - Edinger, Magnus
AU - Genina, Natalja
AU - Rantanen, Jukka
PY - 2019
Y1 - 2019
N2 - The future health care system will contain an ever expanding number of digital elements. The data stored both at a centralized health care level and at a local, patient level (e.g. on a smartphone) will be core elements when deciding treatment strategies in a health care scenario with Internet of Things (IoT) based elements. The current way of manufacturing pharmaceutical products and related existing logistic solutions are not ready for such a revolution. One of the key challenges is cybersecurity and related robust public key infrastructure (PKI) solution. This work introduces one element of a potential solution at a prototype level: the concept of cryptopharmaceuticals, where pharmaceutical products are connected in a patient-specific blockchain of individual dosage units. This technology is based on the concept where each produced dosage unit has a unique information-rich pattern (IRP). A proof of concept smartphone app was applied to demonstrate the visualization of this blockchain at different levels. This includes the manufacturing of the individualized dosage unit, the patient view for his/her personal blockchain, and integration of these products into a health IoT system. This unbreakable blockchain of personal medication history will provide means to avoid counterfeit products and to enable innovative logistic solutions.
AB - The future health care system will contain an ever expanding number of digital elements. The data stored both at a centralized health care level and at a local, patient level (e.g. on a smartphone) will be core elements when deciding treatment strategies in a health care scenario with Internet of Things (IoT) based elements. The current way of manufacturing pharmaceutical products and related existing logistic solutions are not ready for such a revolution. One of the key challenges is cybersecurity and related robust public key infrastructure (PKI) solution. This work introduces one element of a potential solution at a prototype level: the concept of cryptopharmaceuticals, where pharmaceutical products are connected in a patient-specific blockchain of individual dosage units. This technology is based on the concept where each produced dosage unit has a unique information-rich pattern (IRP). A proof of concept smartphone app was applied to demonstrate the visualization of this blockchain at different levels. This includes the manufacturing of the individualized dosage unit, the patient view for his/her personal blockchain, and integration of these products into a health IoT system. This unbreakable blockchain of personal medication history will provide means to avoid counterfeit products and to enable innovative logistic solutions.
KW - app design, blockchain, cryptopharmaceuticals, Internet of Things (IoT), quick response (QR) codes, printed medicine, serialization
U2 - 10.1016/j.xphs.2019.04.025
DO - 10.1016/j.xphs.2019.04.025
M3 - Journal article
VL - 108
SP - 2838
EP - 2841
JO - Journal of Pharmaceutical Sciences
JF - Journal of Pharmaceutical Sciences
SN - 0022-3549
IS - 9
ER -
ID: 217551733