Continuation of growth hormone therapy versus placebo in transition-phase patients with growth hormone deficiency: impact on body composition, insulin sensitivity, and thyroid function
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning
In a placebo-controlled, parallel study of 18 patients with a mean age of 20 years who had confirmed growth hormone (GH) deficiency, we evaluated body composition, insulin sensitivity, and glucose turnover at baseline (when all were receiving GH replacement); after 12 months of continued GH therapy or placebo; and after a 12-month open phase of GH therapy. In the placebo group, insulin sensitivity and fat mass increased and lipid oxidation decreased, whereas glucose oxidation increased (p
Originalsprog | Engelsk |
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Tidsskrift | Journal of Pediatric Endocrinology and Metabolism |
Vol/bind | 15 Suppl 5 |
Sider (fra-til) | 1355-60 |
Antal sider | 6 |
ISSN | 0334-018X |
Status | Udgivet - 2002 |
ID: 48484118