Conservation of the Type IV secretion system throughout Wolbachia evolution

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Standard

Conservation of the Type IV secretion system throughout Wolbachia evolution. / Pichon, Samuel; Bouchon, Didier; Cordaux, Richard; Chen, Lanming; Garrett, Roger A; Grève, Pierre.

I: Biochemical and Biophysical Research Communications, Bind 385, Nr. 4, 2009, s. 557-62.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Pichon, S, Bouchon, D, Cordaux, R, Chen, L, Garrett, RA & Grève, P 2009, 'Conservation of the Type IV secretion system throughout Wolbachia evolution', Biochemical and Biophysical Research Communications, bind 385, nr. 4, s. 557-62. https://doi.org/10.1016/j.bbrc.2009.05.118

APA

Pichon, S., Bouchon, D., Cordaux, R., Chen, L., Garrett, R. A., & Grève, P. (2009). Conservation of the Type IV secretion system throughout Wolbachia evolution. Biochemical and Biophysical Research Communications, 385(4), 557-62. https://doi.org/10.1016/j.bbrc.2009.05.118

Vancouver

Pichon S, Bouchon D, Cordaux R, Chen L, Garrett RA, Grève P. Conservation of the Type IV secretion system throughout Wolbachia evolution. Biochemical and Biophysical Research Communications. 2009;385(4):557-62. https://doi.org/10.1016/j.bbrc.2009.05.118

Author

Pichon, Samuel ; Bouchon, Didier ; Cordaux, Richard ; Chen, Lanming ; Garrett, Roger A ; Grève, Pierre. / Conservation of the Type IV secretion system throughout Wolbachia evolution. I: Biochemical and Biophysical Research Communications. 2009 ; Bind 385, Nr. 4. s. 557-62.

Bibtex

@article{caff7ba02ce811df8ed1000ea68e967b,
title = "Conservation of the Type IV secretion system throughout Wolbachia evolution",
abstract = "The Type IV Secretion System (T4SS) is an efficient pathway with which bacteria can mediate the transfer of DNA and/or proteins to eukaryotic cells. In Wolbachia pipientis, a maternally inherited obligate endosymbiont of arthropods and nematodes, two operons of vir genes, virB3-B6 and virB8-D4, encoding a T4SS were previously identified and characterized at two separate genomic loci. Using the largest data set of Wolbachia strains studied so far, we show that vir gene sequence and organization are strictly conserved among 37 Wolbachia strains inducing various phenotypes such as cytoplasmic incompatibility, feminization, or oogenesis in their arthropod hosts. In sharp contrast, extensive variation of genomic sequences flanking the virB8-D4 operon suggested its distinct location among Wolbachia genomes. Long term conservation of the T4SS may imply maintenance of a functional effector translocation system in Wolbachia, thereby suggesting the importance for the T4SS in Wolbachia biology and survival inside host cells.",
author = "Samuel Pichon and Didier Bouchon and Richard Cordaux and Lanming Chen and Garrett, {Roger A} and Pierre Gr{\`e}ve",
note = "Keywords: Biological Transport; DNA; Evolution, Molecular; Gene Order; Genome, Bacterial; Operon; Protein Transport; Proteins; Wolbachia",
year = "2009",
doi = "10.1016/j.bbrc.2009.05.118",
language = "English",
volume = "385",
pages = "557--62",
journal = "Biochemical and Biophysical Research Communications",
issn = "0006-291X",
publisher = "Elsevier",
number = "4",

}

RIS

TY - JOUR

T1 - Conservation of the Type IV secretion system throughout Wolbachia evolution

AU - Pichon, Samuel

AU - Bouchon, Didier

AU - Cordaux, Richard

AU - Chen, Lanming

AU - Garrett, Roger A

AU - Grève, Pierre

N1 - Keywords: Biological Transport; DNA; Evolution, Molecular; Gene Order; Genome, Bacterial; Operon; Protein Transport; Proteins; Wolbachia

PY - 2009

Y1 - 2009

N2 - The Type IV Secretion System (T4SS) is an efficient pathway with which bacteria can mediate the transfer of DNA and/or proteins to eukaryotic cells. In Wolbachia pipientis, a maternally inherited obligate endosymbiont of arthropods and nematodes, two operons of vir genes, virB3-B6 and virB8-D4, encoding a T4SS were previously identified and characterized at two separate genomic loci. Using the largest data set of Wolbachia strains studied so far, we show that vir gene sequence and organization are strictly conserved among 37 Wolbachia strains inducing various phenotypes such as cytoplasmic incompatibility, feminization, or oogenesis in their arthropod hosts. In sharp contrast, extensive variation of genomic sequences flanking the virB8-D4 operon suggested its distinct location among Wolbachia genomes. Long term conservation of the T4SS may imply maintenance of a functional effector translocation system in Wolbachia, thereby suggesting the importance for the T4SS in Wolbachia biology and survival inside host cells.

AB - The Type IV Secretion System (T4SS) is an efficient pathway with which bacteria can mediate the transfer of DNA and/or proteins to eukaryotic cells. In Wolbachia pipientis, a maternally inherited obligate endosymbiont of arthropods and nematodes, two operons of vir genes, virB3-B6 and virB8-D4, encoding a T4SS were previously identified and characterized at two separate genomic loci. Using the largest data set of Wolbachia strains studied so far, we show that vir gene sequence and organization are strictly conserved among 37 Wolbachia strains inducing various phenotypes such as cytoplasmic incompatibility, feminization, or oogenesis in their arthropod hosts. In sharp contrast, extensive variation of genomic sequences flanking the virB8-D4 operon suggested its distinct location among Wolbachia genomes. Long term conservation of the T4SS may imply maintenance of a functional effector translocation system in Wolbachia, thereby suggesting the importance for the T4SS in Wolbachia biology and survival inside host cells.

U2 - 10.1016/j.bbrc.2009.05.118

DO - 10.1016/j.bbrc.2009.05.118

M3 - Journal article

C2 - 19486895

VL - 385

SP - 557

EP - 562

JO - Biochemical and Biophysical Research Communications

JF - Biochemical and Biophysical Research Communications

SN - 0006-291X

IS - 4

ER -

ID: 18515166