TY - JOUR

T1 - Comparison of Measured and Estimated GFR for Rivaroxaban Dosing in Hospitalized Older Adults

AU - Iversen, Esben

AU - Hornum, Mads

AU - Houlind, Morten Baltzer

N1 - Funding Information: The authors declare that they have no relevant financial interests. Received May 3, 2023. Direct editorial input from an Associate Editor and a Deputy Editor. Accepted in revised form July 15, 2023.

PY - 2023

Y1 - 2023

N2 - Lyu et al1 evaluated discrepancies between different glomerular filtration rate (GFR) estimating equations among 30,261 patients with atrial fibrillation. In patients with low body mass index (BMI), they observed that GFR was lowest according to estimated creatinine clearance (eCrCl), highest according to estimated GFR (eGFR) indexed to body surface area, and intermediate according to nonindexed eGFR. In patients with high BMI, they observed the opposite trend. However, this conclusion is a mathematical consequence of the equations themselves and does not require any analysis of patient data.2

AB - Lyu et al1 evaluated discrepancies between different glomerular filtration rate (GFR) estimating equations among 30,261 patients with atrial fibrillation. In patients with low body mass index (BMI), they observed that GFR was lowest according to estimated creatinine clearance (eCrCl), highest according to estimated GFR (eGFR) indexed to body surface area, and intermediate according to nonindexed eGFR. In patients with high BMI, they observed the opposite trend. However, this conclusion is a mathematical consequence of the equations themselves and does not require any analysis of patient data.2

U2 - 10.1053/j.ajkd.2023.07.010

DO - 10.1053/j.ajkd.2023.07.010

M3 - Letter

C2 - 37678741

AN - SCOPUS:85176226856

VL - 83

SP - 117

EP - 118

JO - American Journal of Kidney Diseases

JF - American Journal of Kidney Diseases

SN - 0272-6386

IS - 1

ER -