Comorbidity and mortality after hip fracture in nineteen thousand six hundred and eighty two patients aged eighteen to sixty five years in Denmark from 1996 to 2012
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Comorbidity and mortality after hip fracture in nineteen thousand six hundred and eighty two patients aged eighteen to sixty five years in Denmark from 1996 to 2012. / Omari, Adam; Madsen, Christian Medom; Lauritzen, Jes Bruun; Jørgensen, Henrik Løvendahl; Vojdeman, Fie Juhl.
I: International Orthopaedics, Bind 43, 2019, s. 2621–2627.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Comorbidity and mortality after hip fracture in nineteen thousand six hundred and eighty two patients aged eighteen to sixty five years in Denmark from 1996 to 2012
AU - Omari, Adam
AU - Madsen, Christian Medom
AU - Lauritzen, Jes Bruun
AU - Jørgensen, Henrik Løvendahl
AU - Vojdeman, Fie Juhl
PY - 2019
Y1 - 2019
N2 - Purpose: This nationwide study assessed associations between comorbidity and mortality after hip fracture in young and middle-aged patients. Methods: Data on 19,682 patients aged 18 to 65 years were extracted from Danish registries out of 154,047 patients who experienced a hip fracture between 1996 and 2012. Mortality and comorbidity were assessed using information on vital status, hospital admissions, and prescriptions. Results: Of the 19,682 patients 17,722 (90.0%) were middle-aged (40–65 years) and 1960 (10.0%) were young (18–39 years). The 30-day mortality rates were 3.2% (n = 570) and 1.6% (n = 32), respectively. Indicators of multi-trauma (hazard ratio (HR), 3.5 95% confidence interval (CI) [1.6–7.8], n = 2056) and having diabetes (HR, 4.4 [1.2–11.3], n = 59) and heart disease (HR, 4.4[1.3–14.8], n = 57) increased 30-day mortality in the young patients, while having cancer (HR, 5.0 [4.2–5.9], n = 1958) increased 30-day mortality in the middle-aged patients. Conclusion: Heart disease and diabetes were associated with high mortality in the young patients while having cancer was associated with high mortality in the middle-aged patients.
AB - Purpose: This nationwide study assessed associations between comorbidity and mortality after hip fracture in young and middle-aged patients. Methods: Data on 19,682 patients aged 18 to 65 years were extracted from Danish registries out of 154,047 patients who experienced a hip fracture between 1996 and 2012. Mortality and comorbidity were assessed using information on vital status, hospital admissions, and prescriptions. Results: Of the 19,682 patients 17,722 (90.0%) were middle-aged (40–65 years) and 1960 (10.0%) were young (18–39 years). The 30-day mortality rates were 3.2% (n = 570) and 1.6% (n = 32), respectively. Indicators of multi-trauma (hazard ratio (HR), 3.5 95% confidence interval (CI) [1.6–7.8], n = 2056) and having diabetes (HR, 4.4 [1.2–11.3], n = 59) and heart disease (HR, 4.4[1.3–14.8], n = 57) increased 30-day mortality in the young patients, while having cancer (HR, 5.0 [4.2–5.9], n = 1958) increased 30-day mortality in the middle-aged patients. Conclusion: Heart disease and diabetes were associated with high mortality in the young patients while having cancer was associated with high mortality in the middle-aged patients.
KW - Age
KW - Comorbidity
KW - Diabetes
KW - Heart disease
KW - Hip fracture
U2 - 10.1007/s00264-019-04323-z
DO - 10.1007/s00264-019-04323-z
M3 - Journal article
C2 - 30903256
AN - SCOPUS:85064074220
VL - 43
SP - 2621
EP - 2627
JO - International Orthopaedics
JF - International Orthopaedics
SN - 0341-2695
ER -
ID: 223453460