Common polymorphisms in KCNJ5 [corrected] are associated with early-onset lone atrial fibrillation in Caucasians

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Javad Jabbari
Morten S Olesen
Anders G Holst
Jonas B Nielsen
Haunsø, Stig
Svendsen, Jesper Hastrup

The aim of this study was to screen lone atrial fibrillation (AF) patients for mutations in the genes KCNJ2, KCNJ3 and KCNJ5, all encoding potassium channels. Furthermore, we wanted to replicate the prior association of two single-nucleotide polymorphisms (SNPs) in KCNJ5, C171T (rs6590357) and G810T (rs7118824), with lone AF in Han Chinese.

Originalsprog	Engelsk
Tidsskrift	Cardiology
Vol/bind	118
Udgave nummer	2
Sider (fra-til)	116-20
Antal sider	5
ISSN	0008-6312
DOI	https://doi.org/10.1159/000323840
Status	Udgivet - 2011

ID: 40219006