Clinical characteristics and predictors of mechanical ventilation in patients with COVID-19 hospitalized in Southern Brazil
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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Clinical characteristics and predictors of mechanical ventilation in patients with COVID-19 hospitalized in Southern Brazil. / Nader Bastos, Gisele Alsina; Zimmermann de Azambuja, Aline; Polanczyk, Carisi Anne; Dalmas Gräf, Débora; Weschenfelder Zorzo, Isabelle; Gasparetto Macari, Juçara; Schnor Haygert, Lúcia; Nasi, Luiz Antônio; Basso Gazzana, Marcelo; Bessel, Marina; Pitrez, Paulo Márcio; Pinheiro de Oliveira, Roselaine; Comerlato Scotta, Marcelo.
I: Revista Brasileira de Terapia Intensiva, Bind 32, Nr. 4, 2020, s. 487-492.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Clinical characteristics and predictors of mechanical ventilation in patients with COVID-19 hospitalized in Southern Brazil
AU - Nader Bastos, Gisele Alsina
AU - Zimmermann de Azambuja, Aline
AU - Polanczyk, Carisi Anne
AU - Dalmas Gräf, Débora
AU - Weschenfelder Zorzo, Isabelle
AU - Gasparetto Macari, Juçara
AU - Schnor Haygert, Lúcia
AU - Nasi, Luiz Antônio
AU - Basso Gazzana, Marcelo
AU - Bessel, Marina
AU - Pitrez, Paulo Márcio
AU - Pinheiro de Oliveira, Roselaine
AU - Comerlato Scotta, Marcelo
PY - 2020
Y1 - 2020
N2 - Objective: This study aims to describe the clinical characteristics and predictors of mechanical ventilation of adult inpatients with COVID-19 in a single center.Methods: A retrospective cohort study was performed and included adult inpatients hospitalized from March 17th to May 3rd, 2020, who were diagnosed with SARS-CoV-2 infection. Clinical and demographic characteristics were extracted from electronic medical records.Results: Overall, 88 consecutive patients were included in this study. The median age of the patients was 63 years (IQR 49 - 71); 59 (67%) were male, 65 (86%) had a college degree and 67 (76%) had at least one comorbidity. Twenty-nine (33%) patients were admitted to the intensive care unit, 18 (20%) patients needed mechanical ventilation, and 9 (10.2%) died during hospitalization. The median length of stay in the intensive care unit and the median duration of mechanical ventilation was 23 and 29.5 days, respectively. An age ≥ 65 years was an independent risk factor for mechanical ventilation (OR 8.4 95%CI 1.3 - 55.6 p = 0.02).Conclusion: Our findings describe the first wave of Brazilian patients hospitalized for COVID-19. Age was the strongest predictor of respiratory insufficiency and the need for mechanical ventilation in our population.
AB - Objective: This study aims to describe the clinical characteristics and predictors of mechanical ventilation of adult inpatients with COVID-19 in a single center.Methods: A retrospective cohort study was performed and included adult inpatients hospitalized from March 17th to May 3rd, 2020, who were diagnosed with SARS-CoV-2 infection. Clinical and demographic characteristics were extracted from electronic medical records.Results: Overall, 88 consecutive patients were included in this study. The median age of the patients was 63 years (IQR 49 - 71); 59 (67%) were male, 65 (86%) had a college degree and 67 (76%) had at least one comorbidity. Twenty-nine (33%) patients were admitted to the intensive care unit, 18 (20%) patients needed mechanical ventilation, and 9 (10.2%) died during hospitalization. The median length of stay in the intensive care unit and the median duration of mechanical ventilation was 23 and 29.5 days, respectively. An age ≥ 65 years was an independent risk factor for mechanical ventilation (OR 8.4 95%CI 1.3 - 55.6 p = 0.02).Conclusion: Our findings describe the first wave of Brazilian patients hospitalized for COVID-19. Age was the strongest predictor of respiratory insufficiency and the need for mechanical ventilation in our population.
UR - https://doi.org/10.5935/0103-507X.20200082
U2 - 10.5935/0103-507x.20200082
DO - 10.5935/0103-507x.20200082
M3 - Journal article
VL - 32
SP - 487
EP - 492
JO - Revista Brasileira de Terapia Intensiva
JF - Revista Brasileira de Terapia Intensiva
SN - 0103-507X
IS - 4
ER -
ID: 323452315