C/EBPalpha in leukemogenesis: Identity and origin of the leukemia-initiating cell

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Standard

C/EBPalpha in leukemogenesis: Identity and origin of the leukemia-initiating cell. / Schuster, Mikkel Bruhn; Porse, Bo Torben.

I: BioFactors, Bind 35, Nr. 3, 2009, s. 227-31.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Schuster, MB & Porse, BT 2009, 'C/EBPalpha in leukemogenesis: Identity and origin of the leukemia-initiating cell', BioFactors, bind 35, nr. 3, s. 227-31. https://doi.org/10.1002/biof.36

APA

Schuster, M. B., & Porse, B. T. (2009). C/EBPalpha in leukemogenesis: Identity and origin of the leukemia-initiating cell. BioFactors, 35(3), 227-31. https://doi.org/10.1002/biof.36

Vancouver

Schuster MB, Porse BT. C/EBPalpha in leukemogenesis: Identity and origin of the leukemia-initiating cell. BioFactors. 2009;35(3):227-31. https://doi.org/10.1002/biof.36

Author

Schuster, Mikkel Bruhn ; Porse, Bo Torben. / C/EBPalpha in leukemogenesis: Identity and origin of the leukemia-initiating cell. I: BioFactors. 2009 ; Bind 35, Nr. 3. s. 227-31.

Bibtex

@article{6a14c440625d11de8bc9000ea68e967b,
title = "C/EBPalpha in leukemogenesis: Identity and origin of the leukemia-initiating cell",
abstract = "The role of the transcription factor CCATT/enhancer binding protein alpha (C/EBPalpha) as a lineage instructive determinant in myelopoiesis is widely accepted. Furthermore, early mutational events ultimately leading to acute myeloid leukemia (AML) often involve abrogation of C/EBPalpha expression and/or function. The main focus of this review is the progression from a preclinical state to AML, and which preleukemic cell population(s) might-in general and in particular in patients with CEBPA mutations-be a target for the secondary genetic and epigenetic events leading to this progression. (c) 2009 International Union of Biochemistry and Molecular Biology, Inc.",
author = "Schuster, {Mikkel Bruhn} and Porse, {Bo Torben}",
year = "2009",
doi = "10.1002/biof.36",
language = "English",
volume = "35",
pages = "227--31",
journal = "BioFactors",
issn = "0951-6433",
publisher = "Wiley",
number = "3",

}

RIS

TY - JOUR

T1 - C/EBPalpha in leukemogenesis: Identity and origin of the leukemia-initiating cell

AU - Schuster, Mikkel Bruhn

AU - Porse, Bo Torben

PY - 2009

Y1 - 2009

N2 - The role of the transcription factor CCATT/enhancer binding protein alpha (C/EBPalpha) as a lineage instructive determinant in myelopoiesis is widely accepted. Furthermore, early mutational events ultimately leading to acute myeloid leukemia (AML) often involve abrogation of C/EBPalpha expression and/or function. The main focus of this review is the progression from a preclinical state to AML, and which preleukemic cell population(s) might-in general and in particular in patients with CEBPA mutations-be a target for the secondary genetic and epigenetic events leading to this progression. (c) 2009 International Union of Biochemistry and Molecular Biology, Inc.

AB - The role of the transcription factor CCATT/enhancer binding protein alpha (C/EBPalpha) as a lineage instructive determinant in myelopoiesis is widely accepted. Furthermore, early mutational events ultimately leading to acute myeloid leukemia (AML) often involve abrogation of C/EBPalpha expression and/or function. The main focus of this review is the progression from a preclinical state to AML, and which preleukemic cell population(s) might-in general and in particular in patients with CEBPA mutations-be a target for the secondary genetic and epigenetic events leading to this progression. (c) 2009 International Union of Biochemistry and Molecular Biology, Inc.

U2 - 10.1002/biof.36

DO - 10.1002/biof.36

M3 - Journal article

C2 - 19322763

VL - 35

SP - 227

EP - 231

JO - BioFactors

JF - BioFactors

SN - 0951-6433

IS - 3

ER -

ID: 12866381