CDKN2A-mutation hos en familie med arveligt malignt melanom
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Malignant melanoma (MM) is a frequent form of cancer with increasing incidence. 6-10% of patients with MM report a family history of MM, and in most populations 2% of unselected cases of MM carry a CDKN2A mutation. tvWe present a family with 24 cases of MM in nine persons from several generations, caused by a previously undescribed germ-line intronic mutation in CDKN2A. Through genetic counselling and genetic testing high-risk persons in the family are located and offered regular screening for MM.
Bidragets oversatte titel | CDKN2A-mutation in a family with hereditary malignant melanoma. |
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Originalsprog | Dansk |
Tidsskrift | Ugeskrift for Laeger |
Vol/bind | 176 |
Udgave nummer | 40 |
Sider (fra-til) | 2-3 |
Antal sider | 2 |
ISSN | 0041-5782 |
Status | Udgivet - 29 sep. 2014 |
ID: 137379405