Bone marrow adipose tissue: Role in bone remodeling and energy metabolism

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Standard

Bone marrow adipose tissue : Role in bone remodeling and energy metabolism. / Tencerova, Michaela; Ferencakova, Michaela; Kassem, Moustapha.

I: Best Practice and Research: Clinical Endocrinology and Metabolism, Bind 35, Nr. 4, 101545, 2021.

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Harvard

Tencerova, M, Ferencakova, M & Kassem, M 2021, 'Bone marrow adipose tissue: Role in bone remodeling and energy metabolism', Best Practice and Research: Clinical Endocrinology and Metabolism, bind 35, nr. 4, 101545. https://doi.org/10.1016/j.beem.2021.101545

APA

Tencerova, M., Ferencakova, M., & Kassem, M. (2021). Bone marrow adipose tissue: Role in bone remodeling and energy metabolism. Best Practice and Research: Clinical Endocrinology and Metabolism, 35(4), [101545]. https://doi.org/10.1016/j.beem.2021.101545

Vancouver

Tencerova M, Ferencakova M, Kassem M. Bone marrow adipose tissue: Role in bone remodeling and energy metabolism. Best Practice and Research: Clinical Endocrinology and Metabolism. 2021;35(4). 101545. https://doi.org/10.1016/j.beem.2021.101545

Author

Tencerova, Michaela ; Ferencakova, Michaela ; Kassem, Moustapha. / Bone marrow adipose tissue : Role in bone remodeling and energy metabolism. I: Best Practice and Research: Clinical Endocrinology and Metabolism. 2021 ; Bind 35, Nr. 4.

Bibtex

@article{81e678d2ba284fed8d610329fe19fe7b,
title = "Bone marrow adipose tissue: Role in bone remodeling and energy metabolism",
abstract = "Bone marrow adipose tissue (BMAT) has been considered for several decades as a silent bystander that fills empty space left in bone marrow following age-related decrease in hematopoiesis. However, recently new discoveries revealed BMAT as a secretory and metabolically active organ contributing to bone and whole-body energy metabolism. BMAT exhibits metabolic functions distinct from extramedullary adipose depots, relevant to its role in regulation of energy metabolism and its contribution to fracture risk observed in metabolic bone diseases. This review discusses novel insights of BMAT with particular emphasis on its contribution to the regulation of bone homeostasis. We also discuss the role of BMAT in regulation of fuel utilization and energy use that affect skeletal stem cell functions.",
keywords = "bone marrow adipose tissue, bone marrow mesenchymal stem cells, energy metabolism, metabolic pathways",
author = "Michaela Tencerova and Michaela Ferencakova and Moustapha Kassem",
note = "Publisher Copyright: {\textcopyright} 2021",
year = "2021",
doi = "10.1016/j.beem.2021.101545",
language = "English",
volume = "35",
journal = "Best Practice and Research in Clinical Endocrinology and Metabolism",
issn = "1521-690X",
publisher = "Elsevier",
number = "4",

}

RIS

TY - JOUR

T1 - Bone marrow adipose tissue

T2 - Role in bone remodeling and energy metabolism

AU - Tencerova, Michaela

AU - Ferencakova, Michaela

AU - Kassem, Moustapha

N1 - Publisher Copyright: © 2021

PY - 2021

Y1 - 2021

N2 - Bone marrow adipose tissue (BMAT) has been considered for several decades as a silent bystander that fills empty space left in bone marrow following age-related decrease in hematopoiesis. However, recently new discoveries revealed BMAT as a secretory and metabolically active organ contributing to bone and whole-body energy metabolism. BMAT exhibits metabolic functions distinct from extramedullary adipose depots, relevant to its role in regulation of energy metabolism and its contribution to fracture risk observed in metabolic bone diseases. This review discusses novel insights of BMAT with particular emphasis on its contribution to the regulation of bone homeostasis. We also discuss the role of BMAT in regulation of fuel utilization and energy use that affect skeletal stem cell functions.

AB - Bone marrow adipose tissue (BMAT) has been considered for several decades as a silent bystander that fills empty space left in bone marrow following age-related decrease in hematopoiesis. However, recently new discoveries revealed BMAT as a secretory and metabolically active organ contributing to bone and whole-body energy metabolism. BMAT exhibits metabolic functions distinct from extramedullary adipose depots, relevant to its role in regulation of energy metabolism and its contribution to fracture risk observed in metabolic bone diseases. This review discusses novel insights of BMAT with particular emphasis on its contribution to the regulation of bone homeostasis. We also discuss the role of BMAT in regulation of fuel utilization and energy use that affect skeletal stem cell functions.

KW - bone marrow adipose tissue

KW - bone marrow mesenchymal stem cells

KW - energy metabolism

KW - metabolic pathways

U2 - 10.1016/j.beem.2021.101545

DO - 10.1016/j.beem.2021.101545

M3 - Review

C2 - 33966979

AN - SCOPUS:85107042727

VL - 35

JO - Best Practice and Research in Clinical Endocrinology and Metabolism

JF - Best Practice and Research in Clinical Endocrinology and Metabolism

SN - 1521-690X

IS - 4

M1 - 101545

ER -

ID: 271759868