Biofilms can act as plasmid reserves in the absence of plasmid specific selection
Publikation: Bidrag til tidsskrift › Letter › Forskning › fagfællebedømt
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Biofilms can act as plasmid reserves in the absence of plasmid specific selection. / Røder, Henriette Lyng; Trivedi, Urvish; Russel, Jakob; Kragh, Kasper Nørskov; Herschend, Jakob; Thalsø-Madsen, Ida; Tolker-Nielsen, Tim; Bjarnsholt, Thomas; Burmølle, Mette; Madsen, Jonas Stenløkke.
I: npj Biofilms and Microbiomes, Bind 7, 78, 2021.Publikation: Bidrag til tidsskrift › Letter › Forskning › fagfællebedømt
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TY - JOUR
T1 - Biofilms can act as plasmid reserves in the absence of plasmid specific selection
AU - Røder, Henriette Lyng
AU - Trivedi, Urvish
AU - Russel, Jakob
AU - Kragh, Kasper Nørskov
AU - Herschend, Jakob
AU - Thalsø-Madsen, Ida
AU - Tolker-Nielsen, Tim
AU - Bjarnsholt, Thomas
AU - Burmølle, Mette
AU - Madsen, Jonas Stenløkke
PY - 2021
Y1 - 2021
N2 - Plasmids facilitate rapid bacterial adaptation by shuttling a wide variety of beneficial traits across microbial communities. However, under non-selective conditions, maintaining a plasmid can be costly to the host cell. Nonetheless, plasmids are ubiquitous in nature where bacteria adopt their dominant mode of life - biofilms. Here, we demonstrate that biofilms can act as spatiotemporal reserves for plasmids, allowing them to persist even under non-selective conditions. However, under these conditions, spatial stratification of plasmid-carrying cells may promote the dispersal of cells without plasmids, and biofilms may thus act as plasmid sinks.
AB - Plasmids facilitate rapid bacterial adaptation by shuttling a wide variety of beneficial traits across microbial communities. However, under non-selective conditions, maintaining a plasmid can be costly to the host cell. Nonetheless, plasmids are ubiquitous in nature where bacteria adopt their dominant mode of life - biofilms. Here, we demonstrate that biofilms can act as spatiotemporal reserves for plasmids, allowing them to persist even under non-selective conditions. However, under these conditions, spatial stratification of plasmid-carrying cells may promote the dispersal of cells without plasmids, and biofilms may thus act as plasmid sinks.
U2 - 10.1038/s41522-021-00249-w
DO - 10.1038/s41522-021-00249-w
M3 - Letter
C2 - 34620879
VL - 7
JO - n p j Biofilms and Microbomes
JF - n p j Biofilms and Microbomes
SN - 2055-5008
M1 - 78
ER -
ID: 281285064