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Autophagy in major human diseases. / Klionsky, Daniel J.; Petroni, Giulia; Amaravadi, Ravi K.; Baehrecke, Eric H.; Ballabio, Andrea; Boya, Patricia; Bravo-San Pedro, José Manuel; Cadwell, Ken; Cecconi, Francesco; Choi, Augustine M.K.; Choi, Mary E.; Chu, Charleen T.; Codogno, Patrice; Colombo, Maria Isabel; Cuervo, Ana Maria; Deretic, Vojo; Dikic, Ivan; Elazar, Zvulun; Eskelinen, Eeva Liisa; Fimia, Gian Maria; Gewirtz, David A.; Green, Douglas R.; Hansen, Malene; Jäättelä, Marja; Johansen, Terje; Juhász, Gábor; Karantza, Vassiliki; Kraft, Claudine; Kroemer, Guido; Ktistakis, Nicholas T.; Kumar, Sharad; Lopez-Otin, Carlos; Macleod, Kay F.; Madeo, Frank; Martinez, Jennifer; Meléndez, Alicia; Mizushima, Noboru; Münz, Christian; Penninger, Josef M.; Perera, Rushika M; Piacentini, Mauro; Reggiori, Fulvio; Rubinsztein, David C.; Ryan, Kevin M; Sadoshima, Junichi; Santambrogio, Laura; Scorrano, Luca; Simon, Hans Uwe; Simon, Anna Katharina; Simonsen, Anne; Stolz, Alexandra; Tavernarakis, Nektarios; Tooze, Sharon A.; Yoshimori, Tamotsu; Yuan, Junying; Yue, Zhenyu; Zhong, Qing; Galluzzi, Lorenzo; Pietrocola, Federico.
I:
EMBO Journal, Bind 40, e108863, 2021.
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
Harvard
Klionsky, DJ, Petroni, G, Amaravadi, RK, Baehrecke, EH, Ballabio, A, Boya, P, Bravo-San Pedro, JM, Cadwell, K, Cecconi, F, Choi, AMK, Choi, ME, Chu, CT, Codogno, P, Colombo, MI, Cuervo, AM, Deretic, V, Dikic, I, Elazar, Z, Eskelinen, EL, Fimia, GM, Gewirtz, DA, Green, DR, Hansen, M
, Jäättelä, M, Johansen, T, Juhász, G, Karantza, V, Kraft, C, Kroemer, G, Ktistakis, NT, Kumar, S, Lopez-Otin, C, Macleod, KF, Madeo, F, Martinez, J, Meléndez, A, Mizushima, N, Münz, C, Penninger, JM, Perera, RM, Piacentini, M, Reggiori, F, Rubinsztein, DC, Ryan, KM, Sadoshima, J, Santambrogio, L, Scorrano, L, Simon, HU, Simon, AK, Simonsen, A, Stolz, A, Tavernarakis, N, Tooze, SA, Yoshimori, T, Yuan, J, Yue, Z, Zhong, Q, Galluzzi, L & Pietrocola, F 2021, '
Autophagy in major human diseases',
EMBO Journal, bind 40, e108863.
https://doi.org/10.15252/embj.2021108863APA
Klionsky, D. J., Petroni, G., Amaravadi, R. K., Baehrecke, E. H., Ballabio, A., Boya, P., Bravo-San Pedro, J. M., Cadwell, K., Cecconi, F., Choi, A. M. K., Choi, M. E., Chu, C. T., Codogno, P., Colombo, MI., Cuervo, A. M., Deretic, V., Dikic, I., Elazar, Z., Eskelinen, E. L., ... Pietrocola, F. (2021).
Autophagy in major human diseases.
EMBO Journal,
40, [e108863].
https://doi.org/10.15252/embj.2021108863Vancouver
Author
Klionsky, Daniel J. ; Petroni, Giulia ; Amaravadi, Ravi K. ; Baehrecke, Eric H. ; Ballabio, Andrea ; Boya, Patricia ; Bravo-San Pedro, José Manuel ; Cadwell, Ken ; Cecconi, Francesco ; Choi, Augustine M.K. ; Choi, Mary E. ; Chu, Charleen T. ; Codogno, Patrice ; Colombo, Maria Isabel ; Cuervo, Ana Maria ; Deretic, Vojo ; Dikic, Ivan ; Elazar, Zvulun ; Eskelinen, Eeva Liisa ; Fimia, Gian Maria ; Gewirtz, David A. ; Green, Douglas R. ; Hansen, Malene ; Jäättelä, Marja ; Johansen, Terje ; Juhász, Gábor ; Karantza, Vassiliki ; Kraft, Claudine ; Kroemer, Guido ; Ktistakis, Nicholas T. ; Kumar, Sharad ; Lopez-Otin, Carlos ; Macleod, Kay F. ; Madeo, Frank ; Martinez, Jennifer ; Meléndez, Alicia ; Mizushima, Noboru ; Münz, Christian ; Penninger, Josef M. ; Perera, Rushika M ; Piacentini, Mauro ; Reggiori, Fulvio ; Rubinsztein, David C. ; Ryan, Kevin M ; Sadoshima, Junichi ; Santambrogio, Laura ; Scorrano, Luca ; Simon, Hans Uwe ; Simon, Anna Katharina ; Simonsen, Anne ; Stolz, Alexandra ; Tavernarakis, Nektarios ; Tooze, Sharon A. ; Yoshimori, Tamotsu ; Yuan, Junying ; Yue, Zhenyu ; Zhong, Qing ; Galluzzi, Lorenzo ; Pietrocola, Federico. / Autophagy in major human diseases. I: EMBO Journal. 2021 ; Bind 40.
Bibtex
@article{ce94349a9e2a421ba7d32db6826f377a,
title = "Autophagy in major human diseases",
abstract = "Autophagy is a core molecular pathway for the preservation of cellular and organismal homeostasis. Pharmacological and genetic interventions impairing autophagy responses promote or aggravate disease in a plethora of experimental models. Consistently, mutations in autophagy-related processes cause severe human pathologies. Here, we review and discuss preclinical data linking autophagy dysfunction to the pathogenesis of major human disorders including cancer as well as cardiovascular, neurodegenerative, metabolic, pulmonary, renal, infectious, musculoskeletal, and ocular disorders.",
keywords = "aging, cancer, inflammation, metabolic syndromes, neurodegeneration",
author = "Klionsky, {Daniel J.} and Giulia Petroni and Amaravadi, {Ravi K.} and Baehrecke, {Eric H.} and Andrea Ballabio and Patricia Boya and {Bravo-San Pedro}, {Jos{\'e} Manuel} and Ken Cadwell and Francesco Cecconi and Choi, {Augustine M.K.} and Choi, {Mary E.} and Chu, {Charleen T.} and Patrice Codogno and Maria Isabel Colombo and Cuervo, {Ana Maria} and Vojo Deretic and Ivan Dikic and Zvulun Elazar and Eskelinen, {Eeva Liisa} and Fimia, {Gian Maria} and Gewirtz, {David A.} and Green, {Douglas R.} and Malene Hansen and Marja J{\"a}{\"a}ttel{\"a} and Terje Johansen and G{\'a}bor Juh{\'a}sz and Vassiliki Karantza and Claudine Kraft and Guido Kroemer and Ktistakis, {Nicholas T.} and Sharad Kumar and Carlos Lopez-Otin and Macleod, {Kay F.} and Frank Madeo and Jennifer Martinez and Alicia Mel{\'e}ndez and Noboru Mizushima and Christian M{\"u}nz and Penninger, {Josef M.} and Rushika M Perera and Mauro Piacentini and Fulvio Reggiori and Rubinsztein, {David C.} and Kevin M Ryan and Junichi Sadoshima and Laura Santambrogio and Luca Scorrano and Simon, {Hans Uwe} and Simon, {Anna Katharina} and Anne Simonsen and Alexandra Stolz and Nektarios Tavernarakis and Tooze, {Sharon A.} and Tamotsu Yoshimori and Junying Yuan and Zhenyu Yue and Qing Zhong and Lorenzo Galluzzi and Federico Pietrocola",
note = "Publisher Copyright: {\textcopyright} 2021 The Authors. Published under the terms of the CC BY 4.0 license",
year = "2021",
doi = "10.15252/embj.2021108863",
language = "English",
volume = "40",
journal = "E M B O Journal",
issn = "0261-4189",
publisher = "Wiley-Blackwell",
}
RIS
TY - JOUR
T1 - Autophagy in major human diseases
AU - Klionsky, Daniel J.
AU - Petroni, Giulia
AU - Amaravadi, Ravi K.
AU - Baehrecke, Eric H.
AU - Ballabio, Andrea
AU - Boya, Patricia
AU - Bravo-San Pedro, José Manuel
AU - Cadwell, Ken
AU - Cecconi, Francesco
AU - Choi, Augustine M.K.
AU - Choi, Mary E.
AU - Chu, Charleen T.
AU - Codogno, Patrice
AU - Colombo, Maria Isabel
AU - Cuervo, Ana Maria
AU - Deretic, Vojo
AU - Dikic, Ivan
AU - Elazar, Zvulun
AU - Eskelinen, Eeva Liisa
AU - Fimia, Gian Maria
AU - Gewirtz, David A.
AU - Green, Douglas R.
AU - Hansen, Malene
AU - Jäättelä, Marja
AU - Johansen, Terje
AU - Juhász, Gábor
AU - Karantza, Vassiliki
AU - Kraft, Claudine
AU - Kroemer, Guido
AU - Ktistakis, Nicholas T.
AU - Kumar, Sharad
AU - Lopez-Otin, Carlos
AU - Macleod, Kay F.
AU - Madeo, Frank
AU - Martinez, Jennifer
AU - Meléndez, Alicia
AU - Mizushima, Noboru
AU - Münz, Christian
AU - Penninger, Josef M.
AU - Perera, Rushika M
AU - Piacentini, Mauro
AU - Reggiori, Fulvio
AU - Rubinsztein, David C.
AU - Ryan, Kevin M
AU - Sadoshima, Junichi
AU - Santambrogio, Laura
AU - Scorrano, Luca
AU - Simon, Hans Uwe
AU - Simon, Anna Katharina
AU - Simonsen, Anne
AU - Stolz, Alexandra
AU - Tavernarakis, Nektarios
AU - Tooze, Sharon A.
AU - Yoshimori, Tamotsu
AU - Yuan, Junying
AU - Yue, Zhenyu
AU - Zhong, Qing
AU - Galluzzi, Lorenzo
AU - Pietrocola, Federico
N1 - Publisher Copyright:
© 2021 The Authors. Published under the terms of the CC BY 4.0 license
PY - 2021
Y1 - 2021
N2 - Autophagy is a core molecular pathway for the preservation of cellular and organismal homeostasis. Pharmacological and genetic interventions impairing autophagy responses promote or aggravate disease in a plethora of experimental models. Consistently, mutations in autophagy-related processes cause severe human pathologies. Here, we review and discuss preclinical data linking autophagy dysfunction to the pathogenesis of major human disorders including cancer as well as cardiovascular, neurodegenerative, metabolic, pulmonary, renal, infectious, musculoskeletal, and ocular disorders.
AB - Autophagy is a core molecular pathway for the preservation of cellular and organismal homeostasis. Pharmacological and genetic interventions impairing autophagy responses promote or aggravate disease in a plethora of experimental models. Consistently, mutations in autophagy-related processes cause severe human pathologies. Here, we review and discuss preclinical data linking autophagy dysfunction to the pathogenesis of major human disorders including cancer as well as cardiovascular, neurodegenerative, metabolic, pulmonary, renal, infectious, musculoskeletal, and ocular disorders.
KW - aging
KW - cancer
KW - inflammation
KW - metabolic syndromes
KW - neurodegeneration
U2 - 10.15252/embj.2021108863
DO - 10.15252/embj.2021108863
M3 - Review
C2 - 34459017
AN - SCOPUS:85113807620
VL - 40
JO - E M B O Journal
JF - E M B O Journal
SN - 0261-4189
M1 - e108863
ER -
