Asthma and obesity: is weight reduction the key to achieve asthma control?
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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Asthma and obesity : is weight reduction the key to achieve asthma control? / Ulrik, Charlotte S.
I: Current Opinion in Pulmonary Medicine, Bind 22, Nr. 1, 01.2016, s. 69-73.Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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TY - JOUR
T1 - Asthma and obesity
T2 - is weight reduction the key to achieve asthma control?
AU - Ulrik, Charlotte S
PY - 2016/1
Y1 - 2016/1
N2 - PURPOSE OF REVIEW: Obesity has significant negative impact on asthma control and risk of exacerbations. The purpose of this review is to discuss recent studies evaluating the effects of weight reduction on asthma control in obese adults.RECENT FINDINGS: Clinical studies have shown that weight reduction in obese patients is associated with improvements in symptoms, use of controller medication, and asthma-related quality of life together with a reduction in the risk for severe exacerbations. Furthermore, several studies have also revealed improvements in lung function and airway responsiveness, and more recently it has been shown that weight reduction following bariatric surgery has positive impact on small airway function, systemic inflammation and bronchial inflammation in this group of patients, which may explain the observed improvements in symptom control and lung function.SUMMARY: Weight reduction in obese adults with asthma leads to an overall improvement in asthma control, including airway hyperresponsiveness and inflammation. Weight reduction should be a cornerstone in the management of obese patients with asthma.
AB - PURPOSE OF REVIEW: Obesity has significant negative impact on asthma control and risk of exacerbations. The purpose of this review is to discuss recent studies evaluating the effects of weight reduction on asthma control in obese adults.RECENT FINDINGS: Clinical studies have shown that weight reduction in obese patients is associated with improvements in symptoms, use of controller medication, and asthma-related quality of life together with a reduction in the risk for severe exacerbations. Furthermore, several studies have also revealed improvements in lung function and airway responsiveness, and more recently it has been shown that weight reduction following bariatric surgery has positive impact on small airway function, systemic inflammation and bronchial inflammation in this group of patients, which may explain the observed improvements in symptom control and lung function.SUMMARY: Weight reduction in obese adults with asthma leads to an overall improvement in asthma control, including airway hyperresponsiveness and inflammation. Weight reduction should be a cornerstone in the management of obese patients with asthma.
KW - Asthma
KW - Humans
KW - Obesity
KW - Quality of Life
KW - Respiratory Function Tests
KW - Risk Factors
KW - Weight Loss
U2 - 10.1097/MCP.0000000000000226
DO - 10.1097/MCP.0000000000000226
M3 - Review
C2 - 26574719
VL - 22
SP - 69
EP - 73
JO - Current Opinion in Pulmonary Medicine
JF - Current Opinion in Pulmonary Medicine
SN - 1070-5287
IS - 1
ER -
ID: 161269925