Association Between Pulmonary Vascular Volume and Cardiac Structure and Function in Patients With Atrial Fibrillation

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Association Between Pulmonary Vascular Volume and Cardiac Structure and Function in Patients With Atrial Fibrillation. / Nielsen, Anne Bjerg; Skaarup, Kristoffer Grundtvig; Djernæs, Kasper; Duus, Lisa Steen; Espersen, Caroline; Sørensen, Samuel Kiil; Ruwald, Martin Huth; Hansen, Morten Lock; Worck, René Husted; Johannessen, Arne; Hansen, Jim; Nardelli, Pietro; San José Estépar, Rubén; San José Estépar, Raúl; Biering-Sørensen, Tor.

I: American Journal of Cardiology, Bind 205, 2023, s. 182-189.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Nielsen, AB, Skaarup, KG, Djernæs, K, Duus, LS, Espersen, C, Sørensen, SK, Ruwald, MH, Hansen, ML, Worck, RH, Johannessen, A, Hansen, J, Nardelli, P, San José Estépar, R, San José Estépar, R & Biering-Sørensen, T 2023, 'Association Between Pulmonary Vascular Volume and Cardiac Structure and Function in Patients With Atrial Fibrillation', American Journal of Cardiology, bind 205, s. 182-189. https://doi.org/10.1016/j.amjcard.2023.07.119

APA

Nielsen, A. B., Skaarup, K. G., Djernæs, K., Duus, L. S., Espersen, C., Sørensen, S. K., Ruwald, M. H., Hansen, M. L., Worck, R. H., Johannessen, A., Hansen, J., Nardelli, P., San José Estépar, R., San José Estépar, R., & Biering-Sørensen, T. (2023). Association Between Pulmonary Vascular Volume and Cardiac Structure and Function in Patients With Atrial Fibrillation. American Journal of Cardiology, 205, 182-189. https://doi.org/10.1016/j.amjcard.2023.07.119

Vancouver

Nielsen AB, Skaarup KG, Djernæs K, Duus LS, Espersen C, Sørensen SK o.a. Association Between Pulmonary Vascular Volume and Cardiac Structure and Function in Patients With Atrial Fibrillation. American Journal of Cardiology. 2023;205:182-189. https://doi.org/10.1016/j.amjcard.2023.07.119

Author

Nielsen, Anne Bjerg ; Skaarup, Kristoffer Grundtvig ; Djernæs, Kasper ; Duus, Lisa Steen ; Espersen, Caroline ; Sørensen, Samuel Kiil ; Ruwald, Martin Huth ; Hansen, Morten Lock ; Worck, René Husted ; Johannessen, Arne ; Hansen, Jim ; Nardelli, Pietro ; San José Estépar, Rubén ; San José Estépar, Raúl ; Biering-Sørensen, Tor. / Association Between Pulmonary Vascular Volume and Cardiac Structure and Function in Patients With Atrial Fibrillation. I: American Journal of Cardiology. 2023 ; Bind 205. s. 182-189.

Bibtex

@article{a6403ffd0aef4cdea2eab1f322898e44,

title = "Association Between Pulmonary Vascular Volume and Cardiac Structure and Function in Patients With Atrial Fibrillation",

abstract = "Pulmonary vascular abnormalities, quantified from computed tomography scans, have frequently been observed in patients with pulmonary diseases. However, little is known about pulmonary vascular changes in patients with cardiac disease. Thus, we aimed to examine the cardiopulmonary relation in patients with atrial fibrillation (AF) by comparing pulmonary vascular volume (PVV) to echocardiographic measures and AF severity. A total of 742 patients (median age 63 years, 70% men) who underwent ablation for AF were included. Preprocedural cardiac computed tomography was used to measure the total and small-vessel PVV, along with the pulmonary artery to aorta ratio and the degree of emphysema. The association between PVV and echocardiographic parameters was evaluated using a multivariable linear regression analysis. Lower total and small-vessel PVV were associated with more impaired measures of cardiac structure and function, including but not limited to left ventricular ejection fraction and peak atrial longitudinal strain. Patients with reduced total and small-vessel PVV had higher odds of having persistent AF than paroxysmal AF in the unadjusted logistic regression analyses. However, after clinical and echocardiographic adjustments, only reduced small-vessel PVV remained independently associated with persistent AF (odds ratio 1.90, 95% confidence interval 1.26 to 2.87, p = 0.002). In conclusion, pulmonary vascular remodeling is associated with persistent AF and with more impaired measures of cardiac structure and function, providing further insights into heart-lung interactions in this patient group.",

keywords = "atrial fibrillation, computed tomography, pulmonary vascular volume, transthoracic echocardiography",

author = "Nielsen, {Anne Bjerg} and Skaarup, {Kristoffer Grundtvig} and Kasper Djern{\ae}s and Duus, {Lisa Steen} and Caroline Espersen and S{\o}rensen, {Samuel Kiil} and Ruwald, {Martin Huth} and Hansen, {Morten Lock} and Worck, {Ren{\'e} Husted} and Arne Johannessen and Jim Hansen and Pietro Nardelli and {San Jos{\'e} Est{\'e}par}, Rub{\'e}n and {San Jos{\'e} Est{\'e}par}, Ra{\'u}l and Tor Biering-S{\o}rensen",

note = "Publisher Copyright: {\textcopyright} 2023 The Author(s)",

year = "2023",

doi = "10.1016/j.amjcard.2023.07.119",

language = "English",

volume = "205",

pages = "182--189",

journal = "Am. J. Cardiol.",

issn = "0002-9149",

publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Association Between Pulmonary Vascular Volume and Cardiac Structure and Function in Patients With Atrial Fibrillation

AU - Nielsen, Anne Bjerg

AU - Skaarup, Kristoffer Grundtvig

AU - Djernæs, Kasper

AU - Duus, Lisa Steen

AU - Espersen, Caroline

AU - Sørensen, Samuel Kiil

AU - Ruwald, Martin Huth

AU - Hansen, Morten Lock

AU - Worck, René Husted

AU - Johannessen, Arne

AU - Hansen, Jim

AU - Nardelli, Pietro

AU - San José Estépar, Rubén

AU - San José Estépar, Raúl

AU - Biering-Sørensen, Tor

PY - 2023

Y1 - 2023

N2 - Pulmonary vascular abnormalities, quantified from computed tomography scans, have frequently been observed in patients with pulmonary diseases. However, little is known about pulmonary vascular changes in patients with cardiac disease. Thus, we aimed to examine the cardiopulmonary relation in patients with atrial fibrillation (AF) by comparing pulmonary vascular volume (PVV) to echocardiographic measures and AF severity. A total of 742 patients (median age 63 years, 70% men) who underwent ablation for AF were included. Preprocedural cardiac computed tomography was used to measure the total and small-vessel PVV, along with the pulmonary artery to aorta ratio and the degree of emphysema. The association between PVV and echocardiographic parameters was evaluated using a multivariable linear regression analysis. Lower total and small-vessel PVV were associated with more impaired measures of cardiac structure and function, including but not limited to left ventricular ejection fraction and peak atrial longitudinal strain. Patients with reduced total and small-vessel PVV had higher odds of having persistent AF than paroxysmal AF in the unadjusted logistic regression analyses. However, after clinical and echocardiographic adjustments, only reduced small-vessel PVV remained independently associated with persistent AF (odds ratio 1.90, 95% confidence interval 1.26 to 2.87, p = 0.002). In conclusion, pulmonary vascular remodeling is associated with persistent AF and with more impaired measures of cardiac structure and function, providing further insights into heart-lung interactions in this patient group.

AB - Pulmonary vascular abnormalities, quantified from computed tomography scans, have frequently been observed in patients with pulmonary diseases. However, little is known about pulmonary vascular changes in patients with cardiac disease. Thus, we aimed to examine the cardiopulmonary relation in patients with atrial fibrillation (AF) by comparing pulmonary vascular volume (PVV) to echocardiographic measures and AF severity. A total of 742 patients (median age 63 years, 70% men) who underwent ablation for AF were included. Preprocedural cardiac computed tomography was used to measure the total and small-vessel PVV, along with the pulmonary artery to aorta ratio and the degree of emphysema. The association between PVV and echocardiographic parameters was evaluated using a multivariable linear regression analysis. Lower total and small-vessel PVV were associated with more impaired measures of cardiac structure and function, including but not limited to left ventricular ejection fraction and peak atrial longitudinal strain. Patients with reduced total and small-vessel PVV had higher odds of having persistent AF than paroxysmal AF in the unadjusted logistic regression analyses. However, after clinical and echocardiographic adjustments, only reduced small-vessel PVV remained independently associated with persistent AF (odds ratio 1.90, 95% confidence interval 1.26 to 2.87, p = 0.002). In conclusion, pulmonary vascular remodeling is associated with persistent AF and with more impaired measures of cardiac structure and function, providing further insights into heart-lung interactions in this patient group.

KW - atrial fibrillation

KW - computed tomography

KW - pulmonary vascular volume

KW - transthoracic echocardiography

UR - http://www.scopus.com/inward/record.url?scp=85168525692&partnerID=8YFLogxK

U2 - 10.1016/j.amjcard.2023.07.119

DO - 10.1016/j.amjcard.2023.07.119

M3 - Journal article

C2 - 37604065

AN - SCOPUS:85168525692

VL - 205

SP - 182

EP - 189

JO - Am. J. Cardiol.

JF - Am. J. Cardiol.

SN - 0002-9149

ER -

ID: 365959832